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  1. No Access

    Article

    Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer

    Targeting tyrosine kinase receptors that share the feedback inhibitor PTPN12 leads to broad spectrum therapeutic suppression of triple-negative breast cancer.

    Amritha Nair, Hsiang-Ching Chung, Tingting Sun, Siddhartha Tyagi… in Nature Medicine (2018)

  2. Article

    Open Access

    A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

    Tumor cells disseminate early in tumor development making metastasis-prevention strategies difficult. Identifying proteins that promote the outgrowth of disseminated tumor cells may provide opportunities for n...

    Emily Powell, Jiansu Shao, Hector M. Picon, Christopher Bristow… in npj Breast Cancer (2018)

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