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  1. No Access

    Article

    Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer

    Advances in high-throughput, genome-wide profiling technologies have allowed for an unprecedented view of the cancer genome landscape. Specifically, high-density microarrays and sequencing-based strategies hav...

    Raj Chari, Kelsie L. Thu, Ian M. Wilson… in Cancer and Metastasis Reviews (2010)

  2. Article

    Open Access

    Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer

    Reactive oxygen species contribute to normal thyroid function. The NRF2 oxidative response pathway is frequently and constitutively activated in multiple tumor types, including papillary thyroid carcinoma (PTC...

    Victor D Martinez, Emily A Vucic, Larissa A Pikor, Kelsie L Thu… in Molecular Cancer (2013)

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  3. Article

    Open Access

    Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology

    Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhib...

    Emily A Vucic, Kelsie L Thu, Larissa A Pikor, Katey SS Enfield, John Yee… in BMC Cancer (2014)

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  4. No Access

    Article

    Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients

    To identify potential biomarkers that may provide new therapeutic targets or prognostic indicators for non-small cell lung cancer (NSCLC), we investigated the three-dimensional (3D) organization of telomeres ...

    Patrapim Sunpaweravong, Kelsie L. Thu… in Journal of Cancer Research and Clinical On… (2016)