4 Result(s)
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Kelsie L. Thu
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessUnique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology
Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues are largely uncharted. We analyzed 6,260 h...
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Article
Open AccessGene isoforms as expression-based biomarkers predictive of drug response in vitro
Next-generation sequencing technologies have recently been used in pharmacogenomic studies to characterize large panels of cancer cell lines at the genomic and transcriptomic levels. Among these technologies, ...
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Article
Open AccessAuthor Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro
In the original version of this Article, financial support was not fully acknowledged. This error has now been corrected in both the PDF and HTML versions of the Article.
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Article
Open AccessThe Antiarrhythmic Drug, Dronedarone, Demonstrates Cytotoxic Effects in Breast Cancer Independent of Thyroid Hormone Receptor Alpha 1 (THRα1) Antagonism
Previous research has suggested that thyroid hormone receptor alpha 1 (THRα1), a hormone responsive splice variant, may play a role in breast cancer progression. Whether THRα1 can be exploited for anti-cancer ...
