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  1. Article

    Open Access

    Comparable type I interferon score determination from PAXgene and Tempus whole blood RNA collection and isolation systems

    Type I interferons (IFN) have important roles in many immune-mediated inflammatory diseases (IMIDs) and are a relatively new therapeutic target. Direct detection of type I IFNs has proved challenging, thus the...

    Lovro Lamot, Iwona Niemietz, Kelly L. Brown in BMC Research Notes (2019)

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  2. Article

    Open Access

    Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity

    Activation of Toll-like receptors (TLRs) is widely accepted as an essential event for defence against infection. Many TLRs utilize a common signalling pathway that relies on activation of the kinase IRAK4 and ...

    Kelly L Brown, Reza Falsafi, Winnie Kum, Pamela Hamill… in Journal of Translational Medicine (2010)

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