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Article
Open AccessGREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation
Growth regulation by estrogen in breast cancer 1 (GREB1) is involved in hormone-dependent and -independent tumor development (e.g., hepatoblastoma). In this study, we found that a GREB1 splicing variant, isofo...
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Article
Open AccessNANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis
At the beginning of tumorigenesis, newly born cancer cells must successfully avoid attack by the immune system. Although most abnormal cells are efficiently identified and destroyed by the immune system, parti...
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Article
Immunogene therapy using immunomodulating HVJ-E vector augments anti-tumor effects in murine malignant glioma
The hemagglutinating virus of Japan envelope (HVJ-E) vector derived from inactivated replication-defective Sendai virus enhances anti-tumor immunity through activation of effector T cells and natural killer (N...