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  1. Article

    Open Access

    GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation

    Growth regulation by estrogen in breast cancer 1 (GREB1) is involved in hormone-dependent and -independent tumor development (e.g., hepatoblastoma). In this study, we found that a GREB1 splicing variant, isofo...

    Koei Shinzawa, Shinji Matsumoto, Ryota Sada, Akikazu Harada, Kaori Saitoh in Oncogene (2023)

  2. Article

    Open Access

    DNA barcoding and gene expression recording reveal the presence of cancer cells with unique properties during tumor progression

    Tumors comprise diverse cancer cell populations with specific capabilities for adaptation to the tumor microenvironment, resistance to anticancer treatments, and metastatic dissemination. However, whether thes...

    Yuka Umeki, Noriaki Ogawa, Yuko Uegaki, Kotaro Saga in Cellular and Molecular Life Sciences (2022)

  3. Article

    Open Access

    Dual function of SF3B2 on chromatin and RNA to regulate transcription in head and neck squamous cell carcinoma

    RNA is spliced concomitantly with transcription and the process is organized by RNA splicing factors, transcriptional regulators, and chromatin regulators. RNA is spliced in close proximity to transcription ma...

    Koji Kitamura, Hidefumi Suzuki, Ryota Abe, Hidenori Inohara in Cell & Bioscience (2022)