-
Article
Open AccessGREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation
Growth regulation by estrogen in breast cancer 1 (GREB1) is involved in hormone-dependent and -independent tumor development (e.g., hepatoblastoma). In this study, we found that a GREB1 splicing variant, isofo...
-
Article
Open AccessDNA barcoding and gene expression recording reveal the presence of cancer cells with unique properties during tumor progression
Tumors comprise diverse cancer cell populations with specific capabilities for adaptation to the tumor microenvironment, resistance to anticancer treatments, and metastatic dissemination. However, whether thes...
-
Article
Open AccessDual function of SF3B2 on chromatin and RNA to regulate transcription in head and neck squamous cell carcinoma
RNA is spliced concomitantly with transcription and the process is organized by RNA splicing factors, transcriptional regulators, and chromatin regulators. RNA is spliced in close proximity to transcription ma...