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7 Result(s)

within Kazuhiro Shiba Remove this filter Cardiology Remove this filter

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  1. No Access

    Article

    Usefulness of competitive inhibitors of protein binding for improving the pharmacokinetics of 186Re-MAG3-conjugated bisphosphonate (186Re-MAG3-HBP), an agent for treatment of painful bone metastases

    We have developed a 186Re-mercaptoacetylglycylglycylglycine complex-conjugated bisphosphonate (186Re-MAG3-HBP) for the treatment of painful bone metastases. We assumed competitive inhibitors of protein binding to...

    Kazuma Ogawa, Takahiro Mukai, Keiichi Kawai… in European Journal of Nuclear Medicine and M… (2009)

  2. No Access

    Article

    In vitro detection of mdr1 mRNA in murine leukemia cells with 111In-labeled oligonucleotide

    The feasibility of intracellular mdr1 mRNA expression detection with radiolabeled antisense oligonucleotide (ODN) was investigated in the murine leukemia cell line, P388/S, and its subclonal, adriamycin-resistant...

    **gming Bai, Kunihiko Yokoyama… in European Journal of Nuclear Medicine and M… (2004)

  3. No Access

    Article

    Improved survival of mice bearing liver metastases of colon cancer cells treated with a combination of radioimmunotherapy and antiangiogenic therapy

    We attempted to determine whether the combined regimen of radioimmunotherapy (RIT) and antiangiogenic therapy would favorably affect the survival of animals bearing liver metastases of colon cancer cells. Dail...

    Seigo Kinuya, Kunihiko Yokoyama… in European Journal of Nuclear Medicine and M… (2004)

  4. No Access

    Article

    Reduction of 99mTc-sestamibi and 99mTc-tetrofosmin uptake in MRP-expressing breast cancer cells under hypoxic conditions is independent of MRP function

    Hypoxia reduces the uptake of technetium-99m sestamibi (MIBI) in human cancer cell lines. In the current investigation, we attempted to identify the relationship between hypoxia-induced alteration of 99mTc-MIBI a...

    Seigo Kinuya, **ao-Feng Li… in European Journal of Nuclear Medicine and M… (2003)

  5. No Access

    Article

    Local delivery of 131I-MIBG to treat peritoneal neuroblastoma

    Internal radiotherapy involving systemic administration of iodine-131 metaiodobenzylguanidine (131I-MIBG) in neural crest tumours such as neuroblastoma has shown considerable success. Although peritoneal seeding ...

    Seigo Kinuya, **ao-Feng Li… in European Journal of Nuclear Medicine and M… (2003)

  6. No Access

    Article

    Benefits of combined radioimmunotherapy and anti-angiogenic therapy in a liver metastasis model of human colon cancer cells

    The combined use of anti-angiogenic therapy (AT) and radioimmunotherapy (RIT) may improve the therapeutic outcome in patients with cancer lesions. This hypothesis is based on the ability of AT to suppress tum...

    **ao-Feng Li, Seigo Kinuya… in European Journal of Nuclear Medicine and M… (2002)

  7. No Access

    Article

    Discrepancy between blood flow and muscarinic receptor distribution in rat brain after middle cerebral artery occlusion

    To clarify whether muscarinic acetylcholine receptor (mAChR) binding can be a viable muscarinic neuronal marker which provides therapeutic information different from perfusional information in global brain, we...

    Ichiei Kuji, Hiroshi Matsuda, Hisashi Sumiya… in European Journal of Nuclear Medicine (1997)