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Open AccessThyroid disorders induced by immune checkpoint inhibitors
Immune checkpoint inhibitors (ICIs) are a revolutionary class of drugs that powerfully contribute to cancer therapy by harnessing the immune system to fight malignancies. However, their successful use as anti-...
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Article
Female-specific risk factors for cardiovascular disease: an update
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. While it was previously believed that men have greater susceptibility to CVD, recent research suggests that women face an...
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Open AccessThe role of low glycemic index and load diets in medical nutrition therapy for type 2 diabetes: an update
The increasing prevalence of type 2 diabetes mellitus (T2DM) and its microvascular and macrovascular complications necessitate an optimal approach to prevention and management. Medical nutrition therapy serves...
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Article
Open AccessGonadal dysfunction in women with diabetes mellitus
It is well known that both type 1 and type 2 diabetes mellitus (DM) are related to increased risk for cardiovascular (CV) and chronic kidney disease (CKD). However, besides these prominently presented complica...
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Article
Hepatokines: the missing link in the development of insulin resistance and hyperandrogenism in PCOS?
The liver plays a critical role in several metabolic pathways, including the regulation of glucose and lipid metabolism. Non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease worldwi...
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Comparison of salivary cortisol levels between women with functional hypothalamic amenorrhea and healthy women: a pilot study
Functional Hypothalamic Amenorrhea (FHA) has been associated with excessive-chronic stress, eating disorders, and weight loss. A common feature is the increased serum cortisol, but its measurement has many lim...
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Open AccessSmoking during pregnancy and gestational diabetes mellitus: a systematic review and meta-analysis
To investigate whether maternal cigarette smoking during pregnancy is a risk factor for develo** GDM.
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Obesity and hyperandrogenism are implicated with anxiety, depression and food cravings in women with polycystic ovary syndrome
PCOS is associated with mood/eating disorders. Negative body image due to obesity, acne, hirsutism seems to play significant role, but hormonal derangements are probably implicated.
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Open AccessSpleen stiffness: a predictive factor of dismal prognosis in liver cirrhosis
Portal hypertension (PH) is a major complication of liver cirrhosis, as it predisposes to the development of serious clinical manifestations such as ascites, hepatic encephalopathy and variceal bleeding, aggra...
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Thyroid disorders and cardiovascular manifestations: an update
Cardiovascular disease (CVD) remains the leading cause of death worldwide, representing a major health, social, and economic issue. Thyroid disorders are very common and affect >10% of the adult population in ...
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Premature ovarian insufficiency in adolescence: a chance for early diagnosis?
Premature ovarian insufficiency (POI) is typically diagnosed when amenorrhea is combined with high gonadotrophins and hypoestrogenemia in a woman under 40 years of age, although, more rarely, POI can develop i...