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Article
Lack of association of HLA—C alleles with late-onset psoriasis in the northern Polish population
The HLA (human leukocyte antigen) Cw*06 allele demonstrates the strongest association with susceptibility to early-onset psoriasis in most populations. Recent data have indicated that late-onset psoriasis (LOP...
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Allergen-Specific Immunotherapy: Towards Combination Vaccines for Allergic and Infectious Diseases
IgE-mediated allergies affect more than 25% of the population. Allergen-specific immunotherapy (SIT) is an antigen-specific and disease-modifying form of treatment. It is based on the therapeutic administratio...
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Article
Entry of human rhinovirus 89 via ICAM-1 into HeLa epithelial cells is inhibited by actin skeleton disruption and by bafilomycin
HRV89, a major-group rhinovirus, uses intercellular adhesion molecule 1 (ICAM-1) for cell entry, while minor-group HRV2 uses the LDL receptor for clathrin-mediated endocytosis. Entry of HRV89 into HeLa epithel...
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Article
Open AccessInduction of allergen-specific blocking IgG using patch delivered recombinant Bet v 1 in guinea pigs
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Article
Open AccessPreDicta chip-based high resolution diagnosis of rhinovirus-induced wheeze
Rhinovirus (RV) infections are major triggers of acute exacerbations of severe respiratory diseases such as pre-school wheeze, asthma and chronic obstructive pulmonary disease (COPD). The occurrence of numerou...
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Article
Open AccessBetamethasone prevents human rhinovirus- and cigarette smoke- induced loss of respiratory epithelial barrier function
The respiratory epithelium is a barrier against pathogens and allergens and a target for therapy in respiratory allergy, asthma and chronic obstructive pulmonary disease (COPD). We investigated barrier-damagin...
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MUW researcher of the month
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Article
Open AccessDissociation of the respiratory syncytial virus F protein-specific human IgG, IgA and IgM response
Human respiratory syncytial virus (RSV) is one of the most important causes of severe respiratory tract infections in early childhood. The only prophylactic protection is the neutralizing antibody, palivizumab...