3 Result(s)
within
Karen Lemmens
Human Genetics
Microbial Genetics and Genomics
-
Article
Open AccessDISTILLER: a data integration framework to reveal condition dependency of complex regulons in Escherichia coli
We present DISTILLER, a data integration framework for the inference of transcriptional module networks. Experimental validation of predicted targets for the well-studied fumarate nitrate reductase regulator s...
-
Article
Open AccessInferring transcriptional modules from ChIP-chip, motif and microarray data
'ReMoDiscovery' is an intuitive algorithm to correlate regulatory programs with regulators and corresponding motifs to a set of co-expressed genes. It exploits in a concurrent way three independent data source...
-
Article
In silico identification and experimental validation of PmrAB targets in Salmonella typhimuriumby regulatory motif detection
The PmrAB (BasSR) two-component regulatory system is required for Salmonella typhimurium virulence. PmrAB-controlled modifications of the lipopolysaccharide (LPS) layer confer resistance to cationic antibiotic po...
