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Article
Inversion in the H–2 complex of t-haplotypes in mice
Mouse t-haplotypes demonstrate strong linkage disequilibrium between t-lethal genes and specific H–2 types, presumably a result of recombination suppression between t and normal chromosomes1. The observation of f...
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Article
Recombination suppression of mouse t-haplotypes due to chromatin mismatching
We show here that recombination occurs at the normal rate in compound female mice containing two different complementing lethal haplotypes (th17/tw12 where there is a long stretch of homologous t-mutant chromatin...
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Article
Molecular analysis of the genetic relationship of trans interacting factors at the T/t complex
The T/t complex is an extensive genetic region proximal to the H–2 complex on mouse chromosome 17, with multiple effects on embryonic development, spermatogenesis and recombination1–3. Recently, two-dimensional g...
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Article
Human and mouse embryonal carcinoma cells in culture share an embryonic antigen (F9)
THE embryonic membrane antigen F9 has been detected on several lines of mouse embryonal carcinoma (EC) cells as well as on mouse embryos and sperm, but not on any other adult cells tested1. F9 or an antigenically...
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Article
Analogies between embryonic (T/t) antigens and adult major histocompatibility (H-2) antigens
Progress has been made in defining cell surface components specified by the T/t locus in the mouse, both in their expression on sperm and, in the one case studied, on normal embryonic cells and teratocarcinoma. S...