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540 Result(s)
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Article
Open AccessQuantifying impairment and disease severity using AI models trained on healthy subjects
Automatic assessment of impairment and disease severity is a key challenge in data-driven medicine. We propose a framework to address this challenge, which leverages AI models trained exclusively on healthy in...
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Open AccessMutations found in cancer patients compromise DNA binding of the winged helix protein STK19
Serine/threonine protein kinase 19 (STK19) has been reported to phosphorylate and activate oncogenic NRAS to promote melanomagenesis. However, concerns have been raised about whether STK19 is a kinase. STK19 h...
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Open AccessCharacterization and the first complete genome sequence of a novel strain of Bergeyella porcorum isolated from pigs in China
Bergeyella porcorum is a newly identified bacterium that has an ambiguous relationship with pneumonia in pigs. However, few studies have adequately characterized this species.
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Open AccessAnalysis and projections of disease burden for different risk factors and sexes of ischemic stroke in young adults in China
To estimate the rate of death, and disability-adjusted life years (DALYs) and project the disease burden of ischemic stroke due to relevant risk factors in young adults age 20–49 years by sex in China. Data fr...
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Probabilistic Analysis of the Frozen Depth of Soil Foundations Considering Thermal and Hydraulic Coupling by COMSOL
53.5% of China’s territory is seasonally frozen. Along with China’s fast social and economic development, more and more infrastructure facilities, e.g., railways, highways and hydraulic engineering projects, a...
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Jasmonic Acid Mediates Maize (Zea mays L.) Roots Response to Soil Nitrogen Heterogeneity
A heterogeneous distribution of nutrients in the soil always affects the development of crops. In this study, we investigated the molecular mechanisms underlying the formation of phenotypic differences between...
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The Effect of Selenium on Endometrial Repair in Goats with Endometritis at High Cortisol Levels
Endometritis is a common postpartum disease of female animals that causes significant losses to the goat industry. High levels of cortisol induced by various stresses after delivery severely inhibit innate imm...
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Article
A protective role of nintedanib in peritoneal fibrosis through H19–EZH2–KLF2 axis via impeding mesothelial-to-mesenchymal transition
Peritoneal fibrosis (PF), a common complication of long-term peritoneal dialysis, accounts for peritoneal ultrafiltration failure to develop into increased mortality. Nintedanib has previously been shown to pr...
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Steel surface defect detection based on MobileViTv2 and YOLOv8
To address the issue of low detection accuracy of steel surface defects due to complex texture background interference and complex defect morphology, this paper proposes an improved YOLOv8 model based on Mobil...
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Large deformation assessment of the bearing capacity factor for rigid footing: effect of soil heterogeneity
In this paper, the influence of soil spatial variability on the large deformation bearing capacity of rigid footing is presented. The random generalized interpolation material point (RGIMP) method, in which th...
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Research on compliant human–robot interaction based on admittance control strategy for shoulder rehabilitation exoskeleton with CGH self-alignment function
In wearable rehabilitation exoskeleton human–robot interaction, the flexibility of movement is crucial to achieve safe and effective rehabilitation. Based on our previously proposed shoulder rehabilitation exo...
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Open AccessHistorical climate change and vicariance events contributed to the intercontinental disjunct distribution pattern of ash species (Fraxinus, Oleaceae)
The Northern Hemisphere temperate forests exhibit a disjunct distributional pattern in Europe, North America, and East Asia. Here, to reveal the promoter of intercontinental disjunct distribution, Fraxinus was us...
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The effects of low-carbon city pilot policy on urban land green use efficiency: evidence from 284 cities in China
China’s low-carbon city pilot (LCCP) initiative aims at devising and implementing a holistic strategy for fostering environmentally sustainable economic progress. This ambitious and multidimensional transition...
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Article
Open AccessEffect of crystal facets in plasmonic catalysis
While the role of crystal facets is well known in traditional heterogeneous catalysis, this effect has not yet been thoroughly studied in plasmon-assisted catalysis, where attention has primarily focused on pl...
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Open AccessChina’s ecological footprint via biomass import and consumption is increasing
As China’s economic and population demands grow, the need for biomass imports rises, presenting challenges for sustainable development and global ecosystem protection. Here we examine China’s increasing influe...
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Numerical study on dynamic mechanical properties of multi-jointed rock mass under impact loading using continuous-discrete coupling model
The multi-jointed rock mass (MJRM) in mining, tunnel and underground engineering is prone to fracture and destabilization under the disturbance of blasting-induced dynamic wave. Study on dynamic mechanical pro...
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Study on Cyclic Mechanical Behavior and Damage Constitutive of PVA Fiber Recycled Aggregate Concrete
The cyclic mechanical properties and damage evolution of polyvinyl alcohol fiber recycled aggregate concrete (PVA-FRAC) play an important role in predicting the response of recycled aggregate concrete structur...
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Editorial for Special Issue on Commonsense Knowledge and Reasoning: Representation, Acquisition and Applications
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Article
A functional gel polymer electrolyte based on PVDF-HFP/gelatin toward dendrite-free lithium metal batteries
The leakage of liquid electrolyte and the formation of lithium dendrites pose challenges to safety and stability of lithium metal batteries (LMBs). The appearance of gel polymer electrolyte (GPE) has obviously...
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Article
Selenomethionine Inhibits NF-κB-mediated Inflammatory Responses of Bovine Mammary Epithelial Cells Caused by Klebsiella pneumoniae by Increasing Autophagic Flux
Klebsiella pneumoniae (K. pneumoniae) is one of the major pathogens causing bovine clinical mastitis. Autophagy maintains cellular homeostasis and resists excessive inflammation in eukaryotic organisms. Selenomet...