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Chapter
Therapy Regimens Used in Adjuvant and Neoadjuvant Treatment of the Discussed Tumor Types
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Article
Orbital metastases in breast cancer: report of two cases and review of the literature
Intraorbital metastases of solid tumors are a rarely diagnosed clinical condition, even though pathological reports suggest an incidence of up to 30% in cancer patients. We report two cases of intraorbital, ex...
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Article
Primary chemotherapy with doxorubicin and paclitaxel in patients with early breast cancer: final results of a multicenter phase II study
To assess the efficacy and safety of primary systemic treatment with doxorubicin and paclitaxel in patients with early breast cancer.
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Chapter
Mammakarzinom
Das Mammakarzinom stellt mit etwa 23% aller malignen Erkrankungen den häufigsten Tumor der Frau dar, an dem in der westlichen Zivilisation derzeit jede achte bis jede zehnte Frau im Lauf ihres Lebens erkrankt....
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Chapter
Pankreaskarzinom
Der Anteil der Pankreaskarzinome an allen malignen Neoplasien ist 2-3%. Die Inzidenz liegt bei 7-8/100.000 für Frauen und 10-11/100.000 bei Männern. Das Verhältnis erkrankter Frauen zu Männer ist bei unter 40-...
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Chapter
Hochmaligne Non-Hodgkin-Lymphome (NHL)
Die hochmalignen NHL sind eine heterogene Gruppe von Erkrankungen, deren gemeinsames biologisches Merkmal ein aggressives klinische Verhalten ist. Das heißt, dass die Erkrankungen in der Regel rasch fortschrei...
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Article
Relationship between bone marrow angiogenesis and plasma cell infiltration and serum β2-microglobulin levels in patients with multiple myeloma
There is growing evidence that angiogenesis is important not only in solid tumors but also in hematological malignancies. Recently, we found that bone marrow angiogenesis is a prognostic factor for disease-re...
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Article
Coincidence of Gaucher's disease due to a 1226G/1448C mutation and of an immunoglobulin G lambda multiple myeloma with Bence-Jones proteinuria
We report about a 58-year-old female with coexisting type-I Gaucher's disease (GD) and multiple myeloma (MM). The diagnosis of GD was made in early childhood by means of bone marrow biopsy and was recently co...
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Article
Patients with malignant lymphomas experience a higher rate of documented infections than patients with breast cancer after high-dose chemotherapy with autologous peripheral stem cell transplantation
The influence of underlying disease on documented infections has rarely been addressed in patients treated with high-dose chemotherapy (HDCT) and subsequent autologous peripheral blood stem cell transplantati...
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Article
Bone marrow microvessel density is a prognostic factor for survival in patients with multiple myeloma
The importance of neoangiogenesis for the progressive growth and viability of solid tumors is well established. Recently, there has been growing evidence that angiogenesis might also be important in hematolog...
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Article
Primary hepatic or splenic diffuse large B-cell lymphoma and hepatitis C virus infection: a non-fortuitous association?
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Article
Further evidence for oxidant-induced vascular endothelial growth factor up-regulation in the bronchoalveolar lavage fluid of lung cancer patients undergoing radio-chemotherapy
Background: Vascular endothelial growth factor (VEGF) is a potent inducer of physiological and neoplastic blood vessel growth. Moreover, in vitro studies have demonstrated that VEGF can be up-regulated by condit...
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Article
An unusual case of leukemic non-Hodgkin's lymphoma with blastic transformation
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Article
New therapeutic approaches in primary systemic AL amyloidosis
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Article
Eosinophilia during fludarabine treatment of chronic lymphocytic leukemia
Although eosinophilia has been reported as a side effect of purine analogues, there is no report on fludarabine-induced eosinophilia in chronic lymphocytic leukemia (CLL). During chemotherapy with fludarabine...
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Article
Rapid reversal of nephrotic syndrome due to primary systemic AL amyloidosis after VAD and subsequent high-dose chemotherapy with autologous stem cell support
In a patient with nephrotic syndrome, renal biopsy revealed AL amyloid deposits. Monoclonal λ light chains were identified in serum and urine. A low percentage of monoclonal plasma cells was detected in the bo...
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Article
Gemcitabine for palliative treatment in metastatic breast cancer
Gemcitabine is one of the recently developed drugs with a high efficacy in various malignant tumours and a mild toxicity profile. As monochemotherapy in metastatic breast cancer, gemcitabine yielded response ...
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Article
Red cell aplasia and megakaryocytic hypoplasia with elevated counts of CD8-positive lymphocytes after resection of a thymoma responding to cyclosporine
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Article
Phase II studies of 1,2,4-triglycidyluracol (TGU) in solid tumors
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Article
Influence of cytotoxic chemotherapy on survival in patients with metastatic breast cancer