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Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery

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  1. Article

    Open Access

    Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells

    Lentiviral vectors (LVs) provide unique opportunities for the development of immunotherapeutic strategies, as they transduce a variety of cells in situ, including antigen-presenting cells (APCs). Engineering LVs ...

    C Goyvaerts, K De Groeve, J Dingemans, S Van Lint, L Robays, C Heirman… in Gene Therapy (2012)

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