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Article
Open AccessRelationships between longitudinal changes in body composition and bone mineral density in middle-to-older aged Australians
There are limited longitudinal data regarding relationships between changes in body composition and bone mineral density (BMD). In 3671 participants aged 46-70 years at baseline, ∆lean mass was a stronger dete...
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Article
Open AccessCalcaneal quantitative ultrasound is associated with all-cause and cardiovascular disease mortality independent of hip bone mineral density
Osteoporosis has been linked with increased risk of cardiovascular disease previously. However, few studies have detailed bone and vascular information. In a prospective study of older women, we demonstrated h...
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Article
Therapeutic efficacy of zoledronic acid combined with calcitriol in elderly patients receiving total hip arthroplasty or hemiarthroplasty for osteoporotic femoral neck fracture
Zoledronic acid could improve the clinical outcome in elderly patients receiving total hip arthroplasty or hemiarthroplasty for osteoporotic femoral neck fracture in the 1-year prospective study.
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Article
Relationship between visceral adipose tissue and bone mineral density in Australian baby boomers
Adiposity has a complex relationship with bone health. In 4865 Australian baby boomers (2642 females) aged 45–70 years, we found that higher visceral adipose tissue mass is associated with reduced bone density...
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Article
Effects of calcium supplementation on circulating osteocalcin and glycated haemoglobin in older women
One year of calcium supplementation in older women led to modest reductions in total osteocalcin and undercarboxylated osteocalcin (ucOC), with no changes in muscle or fat mass, or glycated haemoglobin. Future...
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Article
Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years
We undertook a systematic review and meta-analysis of published papers assessing dietary protein and bone health. We found little benefit of increasing protein intake for bone health in healthy adults but no i...
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Article
Utility of four sarcopenia criteria for the prediction of falls-related hospitalization in older Australian women
Numerous sarcopenia definitions are not associated with increased falls-related hospitalization risk over 5 years to 9.5 years in older community-dwelling Australian women. Measures of muscle strength and phys...
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Article
Discordance between fat mass index and body mass index is associated with reduced bone mineral density in women but not in men: the Busselton Healthy Ageing Study
The obesity-BMD relationship is complex. In 3045 middle-aged adults, we found that in women (but not men) with discordant fat mass index (FMI)/BMI categories, higher body fat for BMI was associated with lower ...
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Article
Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
The relationships between fat mass and bone mass in young adults are unclear. In 1,183 young Australians, lean body mass had a strong positive relationship with total body bone mass in both genders. Fat mass w...
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Article
Differences in structural geometrical outcomes at the neck of the proximal femur using two-dimensional DXA-derived projection (APEX) and three-dimensional QCT-derived (BIT QCT) techniques
Structural geometric parameters at neck of the proximal femur were obtained using DXA-derived hip structural analysis (APEX 3) and quantitative computed tomography-derived (BIT QCT) techniques in 237 elderly f...
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Article
Open AccessAn in vivo comparison of hip structure analysis (HSA) with measurements obtained by QCT
In a population of elderly women, bone cross-sectional area (CSA), cross-sectional moment of inertia (CSMI), section modulus (Z), femoral neck axis length (FNAL), and width measured with hip structure analysis...
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Protein Effects on Bone and Muscle in Elderly Women
Fractures continue to constitute a major public health problem of aging despite recent evidence that the age-specific rate may be falling.1 The facts that before dying at a median age of approximately 83 years, 5...
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Article
Comparison of QCT-derived and DXA-derived areal bone mineral density and T scores
Two-dimensional areal bone mineral density (aBMD) of the proximal femur measured by three-dimensional quantitative computed tomography (QCT) in 91 elderly women was compared to dual-energy X-ray absorptiometry...
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Article
The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly women
Few studies have evaluated the effects of homocysteine and methylenetetrahydrofolate reductase (MTHFR) genotype on age-related bone loss. In our 5-year cohort study with 1,213 women aged 70–85 years, high homo...
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Article
Relationship between vitamin D status, body composition and physical exercise of adolescent girls in Bei**g
Little is known about the prevalence of actual vitamin D deficiency in healthy school-aged adolescents, particularly in China. The aim of this study was to examine the prevalence of hypovitaminosis D and to id...
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Article
The effects of high potassium consumption on bone mineral density in a prospective cohort study of elderly postmenopausal women
Few studies have investigated the long-term effects of potassium intake on BMD. In a cohort of 266 elderly women, we found that baseline potassium intake as reflected by 24-hour urine potassium excretion had p...
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Article
Soluble 4A11 antigen: a novel mediator of leukocyte-endothelial adhesion and monocyte recruitment in rheumatoid arthritis
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Article
Modulation of VCAM-1 expression with antisense oligonucleotides targeting signalling molecules
