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Open AccessRelationships between longitudinal changes in body composition and bone mineral density in middle-to-older aged Australians
There are limited longitudinal data regarding relationships between changes in body composition and bone mineral density (BMD). In 3671 participants aged 46-70 years at baseline, ∆lean mass was a stronger dete...
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Article
Open AccessHigher Dietary Vitamin K Intake is Associated with Better Physical Function and Lower Long-Term Injurious Falls Risk in Community-Dwelling Older Women
In recent years, a potential beneficial role of Vitamin K in neuromuscular function has been recognised. However, the optimal dietary intake of Vitamin K to support muscle function in the context of falls prev...
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Article
Open AccessCalcaneal quantitative ultrasound is associated with all-cause and cardiovascular disease mortality independent of hip bone mineral density
Osteoporosis has been linked with increased risk of cardiovascular disease previously. However, few studies have detailed bone and vascular information. In a prospective study of older women, we demonstrated h...
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Article
Therapeutic efficacy of zoledronic acid combined with calcitriol in elderly patients receiving total hip arthroplasty or hemiarthroplasty for osteoporotic femoral neck fracture
Zoledronic acid could improve the clinical outcome in elderly patients receiving total hip arthroplasty or hemiarthroplasty for osteoporotic femoral neck fracture in the 1-year prospective study.
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Article
Relationship between visceral adipose tissue and bone mineral density in Australian baby boomers
Adiposity has a complex relationship with bone health. In 4865 Australian baby boomers (2642 females) aged 45–70 years, we found that higher visceral adipose tissue mass is associated with reduced bone density...
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Article
RUNX1-activated upregulation of lncRNA RNCR3 promotes cell proliferation, invasion, and suppresses apoptosis in colorectal cancer via miR-1301-3p/AKT1 axis in vitro and in vivo
Long non-coding RNAs (lncRNAs) have participated in progression of colorectal cancer. This study aims to study the role of RUNX1/RNCR3/miR-1301-3p/AKT1 axis in colorectal cancer.
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Article
Associations between circulating bone-derived hormones lipocalin 2, osteocalcin, and glucose metabolism in acromegaly
The aim was to examine changes in the bone-derived hormone lipocalin 2 (LCN2) levels in patients with active acromegaly and to investigate the potential roles of LCN2 and osteocalcin in glucose metabolism.
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Article
Effects of calcium supplementation on circulating osteocalcin and glycated haemoglobin in older women
One year of calcium supplementation in older women led to modest reductions in total osteocalcin and undercarboxylated osteocalcin (ucOC), with no changes in muscle or fat mass, or glycated haemoglobin. Future...
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Article
Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years
We undertook a systematic review and meta-analysis of published papers assessing dietary protein and bone health. We found little benefit of increasing protein intake for bone health in healthy adults but no i...
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Utility of four sarcopenia criteria for the prediction of falls-related hospitalization in older Australian women
Numerous sarcopenia definitions are not associated with increased falls-related hospitalization risk over 5 years to 9.5 years in older community-dwelling Australian women. Measures of muscle strength and phys...
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Article
The impact of dietary protein or amino acid supplementation on muscle mass and strength in elderly people: Individual participant data and meta-analysis of RCT’s
Increasing protein or amino acid intake has been promoted as a promising strategy to increase muscle mass and strength in elderly people, however, long-term intervention studies show inconsistent findings. The...
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Article
The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network
The LIM protein AJUBA is a scaffold protein participating in the regulation of cell adhesion, mitosis, DNA damage, cell differentiation, proliferation, migration and gene transcription. However, its roles in t...
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Article
Depressive symptoms, body composition and bone mass in young adults: a prospective cohort study
An association between depression and obesity is well recognised, but longitudinal studies of depressive symptoms in adolescents as a predictor of body composition are lacking.
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Discordance between fat mass index and body mass index is associated with reduced bone mineral density in women but not in men: the Busselton Healthy Ageing Study
The obesity-BMD relationship is complex. In 3045 middle-aged adults, we found that in women (but not men) with discordant fat mass index (FMI)/BMI categories, higher body fat for BMI was associated with lower ...
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Open AccessEHMTI-0168. Primary headache associated with sexual activity: fifteen new cases and therapeutic results
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Article
Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults
The relationships between fat mass and bone mass in young adults are unclear. In 1,183 young Australians, lean body mass had a strong positive relationship with total body bone mass in both genders. Fat mass w...
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Article
Under-reporting of energy intake in elderly Australian women is associated with a higher body mass index
Identify the extent of under-reporting of energy intake and the characteristics associated with implausible intakes in elderly women.
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Article
Differences in structural geometrical outcomes at the neck of the proximal femur using two-dimensional DXA-derived projection (APEX) and three-dimensional QCT-derived (BIT QCT) techniques
Structural geometric parameters at neck of the proximal femur were obtained using DXA-derived hip structural analysis (APEX 3) and quantitative computed tomography-derived (BIT QCT) techniques in 237 elderly f...
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Article
Open AccessAn in vivo comparison of hip structure analysis (HSA) with measurements obtained by QCT
In a population of elderly women, bone cross-sectional area (CSA), cross-sectional moment of inertia (CSMI), section modulus (Z), femoral neck axis length (FNAL), and width measured with hip structure analysis...
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Open AccessPre-existing heterologous immunity to poliovirus vaccination may mitigate severity of hand, food and mouth disease caused by EV71