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Article
Lichenoid eruption: a hitherto unknown side effect of levetiracetam
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Article
Open AccessDiversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity
Malaria is one of the most serious infectious diseases in the world. The malaria burden is greatly affected by human immunity, and immune responses vary between populations. Genetic diversity in KIR and HLA-C gen...
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Article
Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria
Malaria is one of the deadliest infectious diseases in the world. Immune responses to Plasmodium falciparum malaria vary among individuals and between populations. Human genetic variation in immune system genes i...
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Article
Open AccessA hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples
Killer Immunoglobulin-like Receptors (KIRs) are surface receptors of natural killer cells that bind to their corresponding Human Leukocyte Antigen (HLA) class I ligands, making them interesting candidate genes...
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Article
Open AccessKiller-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR
The Killer-cell Immunoglobulin-like Receptor (KIR) gene complex has considerable biomedical importance. Patterns of polymorphism in the KIR region include variability in the gene content of haplotypes and dive...
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Article
Open AccessKiller cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population
Killer cell immunoglobulin-like receptor (KIR) genes are expressed by natural killer cells and encoded by a family of genes exhibiting considerable haplotypic and allelic variation. HLA-C molecules, the dominant ...
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Article
Open AccessDeterminants of place of death: a population-based retrospective cohort study
As Canada’s population ages, the location of end of life care (whether at home, extended care facility or hospital) may change depending on the location of death. We carried out a study to identify determinant...
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Article
Open AccessPerinatal outcomes in a South Asian setting with high rates of low birth weight
It is unclear whether the high rates of low birth weight in South Asia are due to poor fetal growth or short pregnancy duration. Also, it is not known whether the traditional focus on preventing low birth weig...