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Article
Open AccessDiversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity
Malaria is one of the most serious infectious diseases in the world. The malaria burden is greatly affected by human immunity, and immune responses vary between populations. Genetic diversity in KIR and HLA-C gen...
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Article
Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria
Malaria is one of the deadliest infectious diseases in the world. Immune responses to Plasmodium falciparum malaria vary among individuals and between populations. Human genetic variation in immune system genes i...
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Article
Open AccessKiller-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR
The Killer-cell Immunoglobulin-like Receptor (KIR) gene complex has considerable biomedical importance. Patterns of polymorphism in the KIR region include variability in the gene content of haplotypes and dive...
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Article
Open AccessKiller cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population
Killer cell immunoglobulin-like receptor (KIR) genes are expressed by natural killer cells and encoded by a family of genes exhibiting considerable haplotypic and allelic variation. HLA-C molecules, the dominant ...