95 Result(s)
within
Junwen **ao
Life Sciences
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Article
Open AccessComplete chloroplast genomes of eight Delphinium taxa (Ranunculaceae) endemic to **njiang, China: insights into genome structure, comparative analysis, and phylogenetic relationships
Delphinium L. represents a taxonomically intricate genus of significant phylogenetic and economic importance in Ranunculaceae. Despite the existence of few chloroplast genome datasets, a comprehensive understandi...
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A Giant Panda’s Skin and Hairs Infection of Nannizzia Gypsum on Lumbosacral Region Successfully Treated by Oral Terbinafine and Topic Naftifine-ketoconazole Cream
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Global meat consumption driver analysis with machine learning methods
The growing global meat consumption has serious consequences on human health, the environment and ultimately impacts global food security. Therefore, identifying the drivers of meat consumption and predicting ...
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Open AccessCorrection: Triglyceride-glucose index in early pregnancy predicts the risk of gestational diabetes: a prospective cohort study
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Impact of grass cover on the soil physicochemical properties in China’s orchards: A meta-analysis
Grass cover in orchards has been proposed as a sustainable management system with greater ecological and economic benefits than open pastures. However, few studies have compared the ecological impact of grass-...
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Open AccessTriglyceride-glucose index in early pregnancy predicts the risk of gestational diabetes: a prospective cohort study
This study aimed to investigate the association between the triglyceride-glucose (TyG) index in early pregnancy and the development of gestational diabetes mellitus (GDM) in the second trimester. The primary o...
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Open AccessA small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at the clinical level. ...
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Open AccessComparative chloroplast genomics of 24 species shed light on the genome evolution and phylogeny of subtribe Coelogyninae (Orchidaceae)
The orchids of the subtribe Coelogyninae are among the most morphologically diverse and economically important groups within the subfamily Epidendroideae. Previous molecular studies have revealed that Coelogyn...
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Correlational analysis of physicochemical indexes, microbial communities, and volatile components in light-flavor Daqu from north and south regions of China
Daqu is of great significance to the brewing process of Baijiu, and there are variations in the light-flavor Baijiu Daqu in different regions. However, few studies have been conducted on light-flavor Daqu from th...
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Effects of drought on non-structural carbohydrates and C, N, and P stoichiometric characteristics of Pinus yunnanensis seedlings
To study non-structural carbohydrate characteristics and nutrient utilization strategies of Pinus yunnanensis under continuous drought conditions, 2-year-old seedlings were planted in pots with appropriate water,...
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Open AccessDisrupting of IGF2BP3-stabilized HK2 mRNA by MYO16-AS1 competitively binding impairs LUAD migration and invasion
Since invasive cancer is associated with poor clinical outcomes, exploring the molecular mechanism underlying LUAD progression is crucial to improve the prognosis of patients with advanced disease. Herein, we ...
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The ester production capacity of Pichia kudriavzevii based on functional annotation of genes
Esters were identified as the primary volatile flavor compounds in Chinese Baijiu, exerting a significant influence on its quality and aroma. This study focused on the yeast strain Pichia kudriavzevii, renowned f...
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Single-cell multi-omics profiling reveals key regulatory mechanisms that poise germinal vesicle oocytes for maturation in pigs
The molecular mechanisms controlling the transition from meiotic arrest to meiotic resumption in mammalian oocytes have not been fully elucidated. Single-cell omics technology provides a new opportunity to dec...
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Open AccessThe prognostic value and immune landscaps of m6A/m5C-related lncRNAs signature in the low grade glioma
N6-methyladenosine (m6A) and 5-methylcytosine (m5C) are the main RNA methylation modifications involved in the oncogenesis of cancer. However, it remains obscure whether m6A/m5C-related long non-coding RNAs (l...
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Potential functions and therapeutic implications of glioma-resident mesenchymal stem cells
Mesenchymal stem cells (MSCs) are emerging crucial regulators in the tumor microenvironment (TME), which contributes to tumor progression and therapeutic resistance. MSCs are considered to be the stromal compo...
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Development and application of a rapid detection method for Clarireedia spp. using loop-mediated isothermal amplification (LAMP) assay
Dollar spot, caused by the ascomycete fungus, Clarireedia spp., is a disease that seriously damages most grass species, especially those grown on golf courses. Early detection and intervention are essential for t...
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Open AccessCorrection: HIF-α activation by the prolyl hydroxylase inhibitor roxadustat suppresses chemoresistant glioblastoma growth by inducing ferroptosis
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Open AccessUSP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP
Esophageal squamous carcinoma (ESCC) is the major subtype of esophageal cancer in China, accounting for 90% of cases. Recent studies revealed that abnormalities in the Hippo/YAP axis are pervasive in ESCC and ...
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Article
A Novel Splicing Mutation c.335–1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2
Mutations of NKX2-5 largely contribute to congenital heart diseases (CHDs), especially atrial septal defect (ASD). We identified a novel heterozygous splicing mutation c.335-1G > A in NKX2-5 gene in an ASD family...
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Open AccessNoradrenergic consolidation of social recognition memory is mediated by β-arrestin–biased signaling in the mouse prefrontal cortex
Social recognition memory (SRM) is critical for maintaining social relationships and increasing the survival rate. The medial prefrontal cortex (mPFC) is an important brain area associated with SRM storage. No...
