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Open AccessUSP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity
Lung squamous cell carcinoma (LUSC) is associated with high mortality and limited targeted therapies. USP13 is one of the most amplified genes in LUSC, yet its role in lung cancer is largely unknown. Here, we ...
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Article
Open AccessUSP13 promotes development and metastasis of high-grade serous ovarian carcinoma in a novel mouse model
Epithelial ovarian cancer is the most lethal gynecologic malignancy and one of the most common causes of cancer mortality among women worldwide. Ubiquitin-Specific Peptidase 13 (USP13) gene copy is strongly am...