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  1. No Access

    Article

    Plasma profiles of inflammatory cytokines in children with moderate to severe traumatic brain injury: a prospective cohort study

    The role of inflammatory cytokines in children with moderate to severe TBI (m-sTBI) is still incompletely understood. We aimed to investigate the associations between early plasma expression profiles of inflam...

    Haixin Huang, Guo Fu, Siwei Lu, Song Chen, Junming Huo… in European Journal of Pediatrics (2024)

  2. No Access

    Article

    Effect of intravenous immunoglobulin on the outcome of children with septic shock in a PICU: a retrospective cohort study

    The therapeutic efficacy of intravenous immuneglobulin (IVIG) on children with septic shock remains uncertain. Therefore, we endeavored to investigate the impact of administering intravenous immunoglobulin (IV...

    Haixin Huang, Jian Chen, Hongxing Dang, Chengjun Liu… in European Journal of Pediatrics (2023)

  3. Article

    Open Access

    Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice

    Mutations in the GABRG2 gene encoding the γ-aminobutyric acid (GABA) A receptor gamma 2 subunit are associated with genetic epilepsy with febrile seizures plus, febrile seizures plus, febrile seizures, and other ...

    **nxiao Li, Shengnan Guo, Siying Xu, Zhang** Chen, Lei Wang… in Cell Death & Disease (2021)

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  4. Article

    Open Access

    ALG13 participates in epileptogenesis via regulation of GABAA receptors in mouse models

    ALG13 (asparagine-linked glycosylation 13) plays crucial roles in the process of N-linked glycosylation. Mutations of the ALG13 gene underlie congenital disorders of glycosylation type I (CDG-I), a rare human ...

    Junming Huo, Shuanglai Ren, Peng Gao, Ding Wan, Shikuo Rong… in Cell Death Discovery (2020)

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