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Article
WDR74 facilitates TGF-β/Smad pathway activation to promote M2 macrophage polarization and diabetic foot ulcer wound healing in mice
Diabetic foot ulcer (DFU) is a devastating component of diabetes progression, leading to decreased quality of life and increased mortality in diabetic patients. The underlying mechanism of DFU is not completel...
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Article
Open AccessHigh glucose-induced STING activation inhibits diabetic wound healing through promoting M1 polarization of macrophages
Diabetic wound (DW) is characterized by elevated pro-inflammatory cytokines and cellular dysfunction consistent with elevated reactive oxygen species (ROS) levels. Recent advances in immunology have dissected ...
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Article
Open AccessIntake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis
Brain impairment is one of a major complication of diabetes. Dietary flavonoids have been recommended to prevent brain damage. Astragalus membranaceus is a herbal medicine commonly used to relieve the complicatio...
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Article
The efficacy and safety of combinations of SGLT2 inhibitors and GLP-1 receptor agonists in the treatment of type 2 diabetes or obese adults: a systematic review and meta-analysis
To evaluate the efficacy and safety of combination therapy with sodium–glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists in the treatment of type 2 diabetes melli...
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Article
Capillary Coated with Layer-by-Layer Assembly of γ-Zirconium Phosphate/ Lysozyme Nanocomposite Film for Open Tubular Capillary Electrochromatography Chiral Separation
A new capillary coating of alternate γ-zirconium phosphate lysozyme fabricated for open-tubular electrochromatography enantioseparation. The chiral compounds D, L-tryptophan tested were enantiomerically resolv...
