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Article
Open AccessPredicting sequence and structural specificities of RNA binding regions recognized by splicing factor SRSF1
RNA-binding proteins (RBPs) play diverse roles in eukaryotic RNA processing. Despite their pervasive functions in coding and noncoding RNA biogenesis and regulation, elucidating the sequence specificities that...
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Article
Open AccessIdentification of cardiomyopathy-related core genes through human metabolic networks and expression data
Cardiomyopathy is a complex type of myocardial disease, and its incidence has increased significantly in recent years. Dilated cardiomyopathy (DCM) and ischemic cardiomyopathy (ICM) are two common and indistin...
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Article
Keystone microbiome in the rhizosphere soil reveals the effect of long-term conservation tillage on crop growth in the Chinese Loess Plateau
Keystone taxa play an important role in soil nutrient cycling and crop growth and can be influenced by soil tillage. We investigated the composition of keystone taxa and their relationships with soil propertie...
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Article
Myokine, a key cytokine for physical exercise to alleviate sarcopenic obesity
Skeletal muscle has a robust endocrine function as a powerful organ and can secrete and release cytokines or polypeptides known as myokines. These myokines have significant regulatory effects on signal transdu...