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  1. Article

    Open Access

    Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma

    Metastasis is the main cause of mortality in renal cell carcinoma (RCC). Circular RNAs (circRNAs) involvement in RCC metastasis has been described, although the underlying mechanisms remain unknown. We evaluat...

    Guannan Shu, Xuanxuan Lu, Yihui Pan, Junjie Cen, Kangbo Huang, Mi Zhou, Jun Lu in Oncogene (2023)

  2. Article

    Open Access

    The putative tumor suppressor microRNA-30a-5p modulates clear cell renal cell carcinoma aggressiveness through repression of ZEB2

    Clear cell renal cell carcinoma (ccRCC), the most common subtype of renal cell carcinoma, can easily invade local tissues and metastasize, and is resistant to currently available treatments. Recent studies pro...

    Zhenhua Chen, Jiaxing Zhang, Zhiling Zhang, Zihao Feng, **huan Wei in Cell Death & Disease (2017)