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156 Result(s)
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Article
A review on nanofiber-based composites for toxic and flammable gas sensing
Nanofibers, due to the characteristics of high porosity, large specific surface area, and high strength and mechanical flexibility, exhibit a great potential for gas sensing as a sensing layer or versatile sup...
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Article
Open AccessCortical lipid metabolic pathway alteration of early Alzheimer’s disease and candidate drugs screen
Lipid metabolism changes occur in early Alzheimer's disease (AD) patients. Yet little is known about metabolic gene changes in early AD cortex.
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Article
A non-residue surface modification strategy for active-targeting fluorescent silica nanoparticles to cellular organelles
Silica nanoparticles (SiNPs) with a chemically modified surface typically have a complicated chemical composition, which can significantly differ from their intended design. In this study, we systematically st...
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Article
Open AccessPrevalence and genotype distribution of HPV infections among women in Chengdu,China
Human papilloma virus (HPV) infection among female is the cause of cervical cancer and genital warts. In China, the HPV vaccination rate and the target population screening rate among females are low, and the ...
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Article
Open AccessCharacterization of T cell receptor repertoire in penile cancer
Tumor-infiltrating lymphocytes (TILs) play a key role in regulating the host immune response and sha** tumor microenvironment. It has been previously shown that T cell infiltration in penile tumors was assoc...
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Article
Storage Life Prediction of Carbon Fiber Composites Based on Electrical Conductivity
Carbon fiber composites are widely used in machine manufacturing because of their excellent characteristics. However, their service life is affected by the surrounding environment. Therefore, it is urgent to e...
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Article
Open AccessPrevalence and genotype distribution of HPV6/11/16/18 infections among 180,276 outpatient females from a Women’s and Children’s Central Hospital, 2015–2021, Chengdu, China
The aims of this study on human papilloma virus (HPV) 6/11/16/18 infection among females in Chengdu were to provide more targeted strategies for the prevention and treatment of cervical cancer and genital wart...
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Article
Open AccessThe diagnostic yield of exome sequencing in liver diseases from a curated gene panel
Exome sequencing (ES) has been used in a variety of clinical settings but there are limited data on its utility for diagnosis and/or prediction of monogenic liver diseases. We developed a curated list of 502 g...
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Article
Correction to: Improved dynamic functional connectivity estimation with an alternating hidden Markov model
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Article
Improved dynamic functional connectivity estimation with an alternating hidden Markov model
Dynamic functional connectivity (DFC) analysis has been widely applied to functional magnetic resonance imaging (fMRI) data to reveal the time-varying functional interactions between brain regions. Although th...
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Article
Open AccessCRNDE mediated hnRNPA2B1 stability facilitates nuclear export and translation of KRAS in colorectal cancer
Development of colorectal cancer (CRC) involves activation of Kirsten rat sarcoma viral oncogene homolog (KRAS) signaling. However, the post-transcriptional regulation of KRAS has yet to be fully characterized...
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Article
Open AccessCLASRP oncogene as a novel target for colorectal cancer
Clk4-associated serine/arginine-rich protein (CLASRP), an alternative splicing regulator, may be involved in the development and progression of cancer by regulating the activity of the CDC-like kinase (Clk) famil...
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Article
Strong aliphatic crosslinked polyureas synthesized through a non-isocyanate route and a Michael addition with an aliphatic bismaleimide
A simple and convenient non-isocyanate route is described to synthesize strong aliphatic crosslinked polyureas (cPUreas). A ring-opening reaction of mixed diamines with ethylene carbonate was carried out at 10...
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Article
Open AccessCPPVec: an accurate coding potential predictor based on a distributed representation of protein sequence
Long non-coding RNAs (lncRNAs) play a crucial role in numbers of biological processes and have received wide attention during the past years. Since the rapid development of high-throughput transcriptome sequen...
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Article
Open AccessExpression of TFRC helps to improve the antineoplastic effect of Ara-C on AML cells through a targeted delivery carrier
Currently, high doses of cytarabine arabinoside (Ara-C)-based combined chemotherapy are commonly used in acute myeloid leukemia (AML) therapy, but severe adverse effects and poor suppression effects in leukemi...
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Article
Evaluation of the kinetics of direct aqueous mineral carbonation of wood combustion ash using modified shrinking core models
The direct aqueous mineral carbonation of wood combustion ash (WCA), which is a representative high-calcium waste from combustion process, was systematically investigated by varying complex operating condition...
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Article
Open AccessAuthor Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits
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Article
Nanoarchitectonics of MnO2 nanotubes as sea urchin-like aggregates for dielectric response and microwave absorption with a wide concentration domain
Designing highly reliable and practical microwave absorbers is one of the most important research directions in the microwave absorbing field. Many absorbents suffer from concentration-sensitivity and environm...
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The Early Stage of Abnormal Aging: Cognitive Impairment
Cognitive impairment has become an important aspect affecting the health and quality of life of middle-aged and elderly people, which is defined as the difficulty of thought processing and leads to memory loss...
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The Late Stage of Abnormal Aging: Dementia
With the growth of the aging population, more age-related diseases endanger the health of the elderly, and therefore more research attention has been put on Alzheimer’s disease and dementia. Dementia does not ...