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Article

MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells

Metabolic reprogramming is a hallmark of cancer, alteration of nucleotide metabolism of hepatocellular carcinoma (HCC) is not well-understood. MYBL2 regulates cell cycle progression and hepatocarcinogenesis, i...

Jun-Zhang Zhao, Wei Wang, Tao Liu, Lei Zhang, De-Zheng Lin, Jia-Yin Yao… in BMC Cancer (2022)