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Notopterygium Incisum Extract Promotes Apoptosis by Preventing the Degradation of BIM in Colorectal Cancer

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  1. Article

    Open Access

    Simultaneous integrated boost intensity-modulated radiotherapy post breast-conserving surgery: clinical efficacy, adverse effects, and cosmetic outcomes in breast cancer patients

    Simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) is an innovative technique delivering a higher dose to the tumor bed while irradiating the entire breast. This study aims to assess the...

    Yong-qiang Bao, Teng-hua Yu, Wei Huang, Qing-feng Mao, Gan-jie Tu, Bin Li in Breast Cancer (2024)

  2. Article

    Open Access

    Spatiotemporal multi-omics: exploring molecular landscapes in aging and regenerative medicine

    Aging and regeneration represent complex biological phenomena that have long captivated the scientific community. To fully comprehend these processes, it is essential to investigate molecular dynamics through ...

    Liu-** Chu, Wen-Jia Wang, **n-Pei Gu, ** Wu, Chen Gao in Military Medical Research (2024)

  3. Article

    Open Access

    Mullerian adenosarcoma of the uterus with MASO: a case report of cervical adenosarcoma in a young female that never had sexual behavior

    Cervical mullerian adenosarcoma is a rare uterine sarcoma, especially in young women. Its pathological features are low-grade malignant tumors with bidirectional differentiation, and the degree of malignancy i...

    Jia-Wei Chen, Ya-Jie Huang, Ling-Lu Wang, Jun-Jiang Liu, Ming-Mei Shi in BMC Women's Health (2024)

  4. Article

    Open Access

    Preoperative chemoradiotherapy in older patients with rectal cancer guided by comprehensive geriatric assessment within a multidisciplinary team—a multicenter phase II trial

    The purpose of this study was to evaluate the safety and efficacy of preoperative concurrent chemoradiotherapy (preCRT) for locally advanced rectal cancer in older people who were classified as “fit” by compre...

    Wen-Yang Liu, Yuan Tang, Ning Li, Yu Tang, Yun-Jie Cheng, Lin Yang in BMC Geriatrics (2024)

  5. Article

    Open Access

    Precise planning based on 3D-printed dry-laboratory models can reduce perioperative complications of laparoscopic surgery for complex hepatobiliary diseases: a preoperative cohort study

    Complications after laparoscopic liver resection (LLR) are important factors affecting the prognosis of patients, especially for complex hepatobiliary diseases. The present study aimed to evaluate the value of...

    Wei-Feng Yao, **ao-Kun Huang, Tian-Wei Fu, Lei **, Cheng-Fei Du in BMC Surgery (2024)

  6. Article

    Open Access

    Specific convulsions and brain damage in children hospitalized for Omicron BA.5 infection: an observational study using two cohorts

    SARS-CoV-2 continues to mutate over time, and reports on children infected with Omicron BA.5 are limited. We aimed to analyze the specific symptoms of Omicron-infected children and to improve patient care.

    Yuan-Yuan Pei, Hong-Li Wang, Gen-Quan Yin, Yi Xu in World Journal of Pediatrics (2024)

  7. Article

    Open Access

    A systematic review on reporting quality of economic evaluations for negotiated glucose-lowering drugs in China national reimbursement drug list

    This study aimed to examine the reporting quality of existing economic evaluations for negotiated glucose-lowering drugs (GLDs) included in China National Reimbursement Drug List (NRDL) using the Consolidated ...

    Shi-Yi Bao, Liu Liu, Fu-Ming Li, Yi Yang, Yan Wei, Hui Shao in BMC Health Services Research (2024)

  8. Article

    Open Access

    Diabetes and osteoporosis: a two-sample mendelian randomization study

    The effects on bone mineral density (BMD)/fracture between type 1 (T1D) and type 2 (T2D) diabetes are unknown. Therefore, we aimed to investigate the causal relationship between the two types of diabetes and B...

    Yu-Dun Qu, Zhao-Hua Zhu, Jia-Xuan Li, Wei Zhang, Qi Chen in BMC Musculoskeletal Disorders (2024)

  9. Article

    Open Access

    Influence of moderate-to-high intensity physical activity on depression levels: a study based on a health survey of Chinese university students

    The study aims to examine how moderate-to-vigorous physical activity (MVPA) affects the severity of depression symptoms among Chinese college students. Additionally, it seeks to analyze the mediating mechanism...

    Bo Li, Wei Jiang, Shan-shan Han, Yu-peng Ye, Ya-xing Li, Hu Lou in BMC Public Health (2024)

  10. Article

    Open Access

    Skin mottling score assesses peripheral tissue hypoperfusion in critically ill patients following cardiac surgery

    Skin mottling is a common manifestation of peripheral tissue hypoperfusion, and its severity can be described using the skin mottling score (SMS). This study aims to evaluate the value of the SMS in detecting ...

    **g-chao Luo, Ming-hao Luo, Yi-jie Zhang, Wen-jun Liu, Guo-guang Ma in BMC Anesthesiology (2024)

  11. Article

    Open Access

    Clinical and molecular characterization of 10 Chinese children with congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency

    The clinical manifestations of nonclassical 11beta-hydroxylase deficiency are very similar to those of non-classical 21-hydroxylase deficiency. For this study, we investigated the relationship between the clin...

    Wen-Li Lu, **ao-Yu Ma, Jiao Zhang, Jun-Qi Wang in World Journal of Pediatrics (2024)

  12. Article

    Open Access

    Effect of early peri-operative arterial lactate concentration level ratios on post-hepatectomy liver failure

    Post-hepatectomy liver failure (PHLF) is a serious complication after hepatectomy and a major cause of death. The current criteria for PHLF diagnosis (ISGLS consensus) require laboratory data of elevated INR l...

    Dong-Dong Wang, Meng-Meng Dong, Ya-Ming **e, Fei-Qi Xu, Tian-Wei Fu in Discover Oncology (2024)

  13. Article

    Open Access

    Effect of neutrophil to lymphocyte ratio on prognosis of elderly patients with severe sepsis combined with diabetes mellitus

    To investigate the predictive value of neutrophil-to-lymphocyte ratio (NLR) in the short-term prognosis of elderly patients with severe sepsis combined with diabetes mellitus (DM).

    Shan **, Jun-bin Yin, Wei Li, Li-li Zang in BMC Geriatrics (2024)

  14. Article

    Open Access

    Risk factors for one-year mortality following discharge in patients with acute aortic dissection: development and validation of a predictive model in a cross-sectional study

    This study was aimed to identify the risk factors that influence the mortality risk in patients with acute aortic dissection (AAD) within one year after discharge, and aimed to construct a predictive model for...

    Ting Zhou, **g-**ao Li, Chao-Yong Zhang, Yu-Gui Li in BMC Cardiovascular Disorders (2024)

  15. Article

    Open Access

    Analysis of influencing factors of HPV vaccination willingness of female sex workers in urban entertainment venues based on the IMB model in Guangxi, China

    Understanding HPV vaccination willingness and its influencing factors among female sex workers (FSWs) in entertainment venues in an urban area of Guangxi, China.

    Zhi-yan He, Jun-hong Wei, Jian-ming Jiang, Rui Hu, Guang-zi Qi in BMC Women's Health (2024)

  16. Article

    Open Access

    Risk factors for postoperative delirium in elderly patients undergoing heart valve surgery with cardiopulmonary bypass

    The aim of this study was to identify the risk factors for postoperative delirium (POD) in elderly patients undergoing heart valve surgery with cardiopulmonary bypass (CPB).

    Na Chen, Yun-chang Mo, Min Xu, Si-si Chen, Wei Gao in Journal of Cardiothoracic Surgery (2024)

  17. Article

    Open Access

    Quality of life, household income, and dietary habits are associated with the risk of sarcopenia among the Chinese elderly

    Health-related quality of life (HRQoL), which can be influenced by various aspects, especially socioeconomic status and lifestyle, has been identified as an important predictor of the prognosis of older adults...

    Hua Wan, Yan-Hui Hu, Wei-Peng Li, Quan Wang in Aging Clinical and Experimental Research (2024)

  18. Article

    Open Access

    Global burden of liver cirrhosis and other chronic liver diseases caused by specific etiologies from 1990 to 2019

    This study aimed to assess the global, regional, and national burden of liver cirrhosis and other chronic liver diseases between 1990 and 2019, considering five etiologies (hepatitis B, hepatitis C, alcohol us...

    **ao-Ning Wu, Feng Xue, Nan Zhang, Wei Zhang, **g-**g Hou, Yi Lv in BMC Public Health (2024)

  19. Article

    Open Access

    Optimal drug regimens for improving ALP biochemical levels in patients with primary biliary cholangitis refractory to UDCA: a systematic review and Bayesian network meta-analysis

    Up to 40% of UDCA-treated patients do not have an adequate clinical response. Farnesoid X receptor agonists, peroxisome proliferator-activated receptor agonists, and fibroblast growth factor 19 analogs were de...

    Wei Lin, Jun-xi Wang, Yi-juan Liu in Systematic Reviews (2024)

  20. Article

    Open Access

    Correction to: Clinical and molecular characterization of 10 Chinese children with congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency

    Wen-Li Lu, **ao-Yu Ma, Jiao Zhang, Jun-Qi Wang in World Journal of Pediatrics (2024)

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