52 Result(s)
within
Biomedicine
Oncology
Jun-**a Wei
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Article
Open AccessBMP-6 promotes E-cadherin expression through repressing δEF1 in breast cancer cells
Bone morphogenetic protein-6 (BMP-6) is critically involved in many developmental processes. Recent studies indicate that BMP-6 is closely related to tumor differentiation and metastasis.
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Open AccessAntioxidant intervention of smoking-induced lung tumor in mice by vitamin E and quercetin
Epidemiological and in vitro studies suggest that antioxidants such as quercetin and vitamin E (VE) can prevent lung tumor caused by smoking; however, there is limited evidence from animal studies.
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Article
Open AccessParthenolide induces proliferation inhibition and apoptosis of pancreatic cancer cells in vitro
To explore the anti-tumor effects of parthenolide in human pancreatic cancer.
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Genetic analysis of the P1 region of human enterovirus 71 strains and expression of the 55 F strainVP1 protein
Enterovirus 71 (EV71) is a member of the Entero-virus genus of the Picornaviridae family and is the major cause of Hand, foot, and mouth disease (HFMD) in children. Different strains from Gansu were cloned and...
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Open AccessFractionated stereotactic radiotherapy for 136 patients with locally residual nasopharyngeal carcinoma
To evaluate the efficacy and toxicity of fractionated stereotactic radiotherapy (FSRT) in patients with residual nasopharyngeal carcinoma (NPC).
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Open AccessFHL1C induces apoptosis in notch1-dependent T-ALL cells through an interaction with RBP-J
Aberrantly activated Notch signaling has been found in more than 50% of patients with T-cell acute lymphoblastic leukemia (T-ALL). Current strategies that employ γ-secretase inhibitors (GSIs) to target Notch a...
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Open AccessThe prognostic importance of jaundice in surgical resection with curative intent for gallbladder cancer
Preoperative jaundice is frequent in gallbladder cancer (GBC) and indicates advanced disease. Resection is rarely recommended to treat advanced GBC. An aggressive surgical approach for advanced GBC remains lac...
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Open AccessElevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction
Natural killer (NK) cells play a key role in non-specific immune response in different cancers, including pancreatic cancer. However the anti-tumor effect of NK cells decreases during pancreatic cancer progres...
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Open AccessRETRACTED ARTICLE: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis
The onset of distal metastasis, which underlies the high mortality of breast cancers, warrants substantial studies to depict its molecular basis. Nuclear factor of activated T cells 5 (NFAT5) is upregulated in...
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Article
Open AccessA pseudogene-signature in glioma predicts survival
Pseudogene was recognized as a potential tumor suppressor or oncogene in varies of diseases, however its roles in glioma have not been investigated. Our study was to identify the pseudogene-signature that pred...
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Open AccessClinical parameters predicting pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer
Preoperative chemoradiotherapy (CRT), followed by total mesorectal excision, has become the standard of care for patients with clinical stages II and III rectal cancer. Patients with pathologic complete respon...
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Open AccessHippo/YAP signaling pathway is involved in osteosarcoma chemoresistance
Osteosarcoma is the most common bone malignancy in children and adolescents, and 20%–30% of the patients suffer from poor prognosis because of individual chemoresistance. The Hippo/yes-associated protein (YAP)...
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Article
Open AccessATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma
Activating transcription factor 2 (ATF2) is a basic helix-loop-helix transcription factor, which has been shown to participate in the pathobiology of numerous cancers. However, the role of ATF2 in renal cell c...
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Open AccessHigh-risk factors of parotid lymph node metastasis in nasopharyngeal carcinoma: a case-control study
Although parotid-sparing IMRT decreased the dose distribution of parotid, parotid region recurrence has been reported. Prophylactic irradiation in parotid area would be necessary in patients with high risk of ...
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Open AccessRETRACTED ARTICLE: TLE3 represses colorectal cancer proliferation by inhibiting MAPK and AKT signaling pathways
Transducin-like enhancer of Split3 (TLE3) serves as a transcriptional corepressor during cell differentiation and shows multiple roles in different kinds of cancers. Recently, TLE3 together with many other gen...
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Open AccessRadiation-induced osteosarcoma of the maxilla and mandible after radiotherapy for nasopharyngeal carcinoma
The increasing incidence of radiation-induced osteosarcoma of the maxilla and mandible (RIOSM) has become a significant problem that can limit long-term survival. The purpose of this study was to analyze the a...
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Article
Open AccessHPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instability
The integration of human papilloma virus (HPV) into host genome is one of the critical steps that lead to the progression of precancerous lesion into cancer. However, the mechanisms and consequences of such in...
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Article
Open AccessNOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?
Gastric cancer (GC) ranks the most common cancer types and is one of the leading causes of cancer-related death. Due to delayed diagnosis and high metastatic frequency, 5-year survival rate of GC is rather low...
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Open AccessA prediction model for lymph node metastases using pathologic features in patients intraoperatively diagnosed as stage I non-small cell lung cancer
There is little information on which pattern should be chosen to perform lymph node dissection for stage I non-small-cell lung cancer. This study aimed to develop a model for predicting lymph node metastasis u...
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Open AccessSilencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel
Docetaxel-based chemotherapy failure in advanced prostate carcinoma has partly been attributed to the resistance of prostate cancer (PC) cells to docetaxel-induced apoptosis. Hence, there is an urgent need to ...
