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298 Result(s)
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Article
Hematological study on a case with cerebellar hemangioblastoma associated with erythrocytosis, with special reference to a erythropoiesis-stimulating activity present in the fluid of the cyst of tumor
A case of cerebellar hemangioblastoma associated with slight but definite erythrocytosis is reported. Operative removal of the tumor resulted in the reversion to a normal blood picture. Erythropoietin-like act...
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Article
Phenoty** of malignant hematopoietic cells
1255 cases of leukemia-lymphoma were tested between 1972 and 1984 by multiple marker analysis. Routine leukemia phenoty** was performed using standard morphological and cytochemical techniques in combination...
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Long-term follow-up study of children with chronic ITP
A total of 126 children with chronic idiopathic thrombocytopenic purpura, including 35 splenectomized cases, were investigated in a long-term follow-up study, with regard to residual hematologic and immunologi...
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Article
Immunological regression of metastatic cancer in the liver as a result of “in vivo xenogenization”
We attempted to induce the regression of liver metastatic tumor cellsin vivo by the administration to rats of Friend leukemia virus (FV) (in vivo xenogenization). The virus which was used in this experiment, FV, ...
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Article
Feasibility of conducting a lung-cancer chemoprevention trial among tin miners in Yunnan, P. R. China
Tin miners in Yunnan Province in southern China have an extremely high rate of lung cancer, more than one percent per year among those at ‘high risk’ (40 + years old, with 10 + years of underground mining and/...
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Demonstration of a possible link between high grade malignancy in dimethylbenz[a]anthracene-induced rat mammary carcinoma and increased urokinase plasminogen activator content
Recent reports have suggested that tissue-type plasminogen activator activity is regulated by estrogen in 7,12-dimethylbenz[a]anthracene-induced rat mammary carcinoma type I cells but is not necessarily regula...
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Tissue-type plasminogen activator is involved in skeletal metastasis from human breast cancer
This study was undertaken to determine if primary breast tumor plasminogen activator expression correlates with skeletal metastasis in breast cancer. Total plasminogen activator activity was significantly lowe...
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Retrospective cohort study of risk-factors for esophageal cancer in Linxian, People's Republic of China
A retrospective cohort study of esophageal (including gastric cardia) cancer was conducted to examine dietary and other potential risk factors in Linxian, a high-risk area in P.R. China. Study subjects were id...
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Article
Characterization of the progressive sublines derived from a weakly malignant cloned cell line, ER-1, co-inoculated subcutaneously with a foreign body
We previously established an experimental model of tumor progression using a weakly malignant rat mammary carcinoma cell line, ER-1. Using this model, we demonstrated that ER-1 cells converted into highly tumo...
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Article
Invasion and metastasis of liver cancer: expression of intercellular adhesion molecule 1
To study the relationship between intercellular adhesion molecule 1 (ICAM-1) and liver cancer metastasis and to find predicting factors that could indicate the growth and metastasis of liver cancer. Methods: ICA...
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Article
Different expression patterns of nitric oxide synthase isozymes in various gynecological cancers
The expression of nitric oxide synthase (NOS) in human gynecological cancers, including ovarian cancers, uterocervical cancers, and endometrial cancers for example, was examined by the reverse transcriptase/p...
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Article
Antiangiogenic and antitumor effects of 14-membered ring macrolides on mouse B16 melanoma cells
We examined the effects of macrolide antibiotics on tumor angiogenesis, tumor growth and metastasis in the B16BL6 mouse melanoma and C57BL mouse system. Two 14-membered ring macrolide antibiotics, roxithromyci...
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Article
Induction of c-met proto-oncogene expression at the metastatic site
In metastatic processes, gene expression may variously alter through interactions between tumor and host stromal cells at the metastatic site. Using a tail vein injection-lung metastatic model and differential...
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Article
Expression of leukemia-inhibitory factor as an autocrinal growth factor in human medulloblastomas
Medulloblastoma is the most frequent pediatric brain tumor, with the capacities of rapid proliferation and intracranal dissemination. However, the factor(s) regulating medulloblastoma growth has not yet been ...
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Article
Hepatocyte growth factor promotes migration of human hepatocellular carcinoma via phosphatidylinositol 3-kinase
Hepatocyte growth factor (HGF) is known to be a potent mitogen and motogen for epithelial cells. Hepatocellular carcinoma (HCC) often metastasizes, and the c-Met/HGF receptor is highly expressed by HCC cells. ...
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Article
Activated leukocyte cell adhesion molecule (ALCAM) and annexin II are involved in the metastatic progression of tumor cells after chemotherapy with Adriamycin
Metastasis frequently occurs during and/or after chemotherapy resulting in failure. This suggests that inadequate chemotherapy promotes the emergence of more malignant tumor cells with metastatic potential. Ho...
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Heparin and phentolamine combined, rather than heparin alone, improves hepatic microvascular procurement in a non-heart-beating donor rat-model
Improvement of organ procurement from non-heart-beating donors (NHBDs) could increase the donor organ pool for liver transplantation. Whether anti-coagulative and anti-vasospastic substances can improve hepat...
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Tumor cells as the origin of elevated serum α1,3fucosyltransferase in association with malignancy
We have previously reported that the elevated activities of serum α1,3fucosyltransferase reverted to normal levels after curative removal of the tumors. To determine the origin of elevated serum α1,3fucosyltra...
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A novel tumor-associated mucin of gastrointestinal carcinoma
Purpose: To identify a new tumor-associated antigen, a monoclonal antibody, SC142, was produced by immunizing mice with a stomach cancer cell line. The tumor specificity of mAb SC142 was studied...
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Article
A Prospective Surveillance of Nosocomial Respiratory Syncytial Virus Infection in a Hematology Ward: A Single-Center Experience in Japan
Special thanks to Miss Nakae for the collecting clinical information and to Mr. Takahashi for technical advice on the rapid RSV antigen test.