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2,632 Result(s)
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Open AccessNicotinamide riboside restores nicotinamide adenine dinucleotide levels and alleviates brain injury by inhibiting oxidative stress and neuroinflammation in a mouse model of intracerebral hemorrhage
Hemorrhagic stroke is a global health problem owing to its high morbidity and mortality rates. Nicotinamide riboside is an important precursor of nicotinamide adenine dinucleotide characterized by a high bioav...
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Open AccessIL-27 disturbs lipid metabolism and restrains mitochondrial activity to inhibit γδ T17 cell-mediated skin inflammation
IL-17+ γδ T cells (γδ T17) are kick-starters of inflammation due to their strict immunosurveillance of xenobiotics or cellular damages and rapid response to pro-inflammatory stimulators. IL-27 is a well-recogn...
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Open AccessCorrection: Unveiling the role of HP1α-HDAC1-STAT1 axis as a therapeutic target for HP1α-positive intrahepatic cholangiocarcinoma
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Open AccessAuthor Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice
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Cross-sectional study of hepatitis B virus infection in female breast cancer patients in China for the first time diagnosed
The correlation between breast cancer and hepatitis B virus (HBV) remains inconclusive. This study aims to explore the serological status of HBV infection and past infection in different age groups of female b...
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Open AccessCorrection to: p-Parabolicity and a Generalized Bochner’s Method with Applications
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Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma
The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...
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Cytokines-activated nuclear IKKα-FAT10 pathway induces breast cancer tamoxifen-resistance
Endocrine therapy that blocks estrogen signaling is the most effective treatment for patients with estrogen receptor positive (ER+) breast cancer. However, the efficacy of agents such as tamoxifen (Tam) is often ...
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Open AccessSearch for long-lived heavy neutrinos in the decays of B mesons produced in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for long-lived heavy neutrinos (N) in the decays of B mesons produced in proton-proton collisions at ...
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Open AccessWhich factors are associated with adverse prognosis in multiple myeloma patients after surgery? - preliminary establishment and validation of the nomogram
To investigate the prognosis of patients with Multiple Myeloma (MM) after surgery, analyze the risk factors leading to adverse postoperative outcomes, and establish a nomogram.
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Open AccessNeferine inhibits BMECs pyroptosis and maintains blood–brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α
Blood–brain barrier disruption is a critical pathological event in the progression of ischemic stroke (IS). Most studies regarding the therapeutic potential of neferine (Nef) on IS have focused on neuroprotect...
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Hybrid bimetallic cluster ZrO2/Rh@ N, S co-doped porous carbon nanosheets for efficient hydrogen evolution in acid electrolytes
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Comparison of totally robotic and totally laparoscopic gastrectomy for gastric cancer: a propensity score matching analysis
With the improvements in laparoscopic or robotic surgical techniques and instruments, a growing number of surgeons have attempted to complete all digestive tract reconstruction intracorporeally; these procedur...
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From Perspective of Hippocampal Plasticity: Function of Antidepressant Chinese Medicine **aoyaosan
The hippocampus is one of the most commonly studied brain regions in the context of depression. The volume of the hippocampus is significantly reduced in patients with depression, which severely disrupts hippo...
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Open AccessGWAS combined with QTL map** reveals the genetic loci of leaf morphological characters in Nicotiana tabacum
Leaf morphology plays a crucial role in photosynthetic efficiency and yield potential in crops. Cigar tobacco plants, which are derived from common tobacco (Nicotiana tabacum L.), possess special leaf characteris...
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Open AccessSearch for heavy neutral leptons in final states with electrons, muons, and hadronically decaying tau leptons in proton-proton collisions at \( \sqrt{s} \) = 13 TeV
A search for heavy neutral leptons (HNLs) of Majorana or Dirac type using proton-proton collision data at ...
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Analysis of CCND3 mutations in diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL), accounts for 30–40% of newly diagnosed lymphomas, has an overall cure rate of approximately 60%. Despite previous reports suggesting a negative prognostic association bet...
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Unveiling the Re, Cr, and I diffusion in saturated compacted bentonite using machine-learning methods
The safety assessment of high-level radioactive waste repositories requires a high predictive accuracy for radionuclide diffusion and a comprehensive understanding of the diffusion mechanism. In this study, a ...
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Influence of cooling rate upon weld metal microstructural evolution behaviors of EH36 shipbuilding steel
Microstructural evolution features have been systematically investigated for the weld metal of EH36 shipbuilding steel under an in situ confocal scanning laser microscope. The influence of cooling rate on micr...
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Open AccessSearch for the decay of the Higgs boson to a pair of light pseudoscalar bosons in the final state with four bottom quarks in proton-proton collisions at \( \sqrt{\textrm{s}} \) = 13 TeV
A search is presented for the decay of the 125 GeV Higgs boson (H) to a pair of new light pseudoscalar bosons (a), followed by the prompt decay of each a boson to a bottom quark-antiquark pair,