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  1. No Access

    Article

    Activation of ERK and suppression of calcineurin are interacting mechanisms of cardioprotection afforded by δ-opioid receptor activation

    The aim of this study was to examine possible interactions of ERK and calcineurin in cardioprotection afforded by δ-opioid receptor stimulation. Infarction was induced in rat hearts by 20-min coronary occlusio...

    Yoshihiro Ikeda, Tetsuji Miura, Jun Sakamoto, Takayuki Miki… in Basic Research in Cardiology (2006)

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    Article

    Interruption of signal transduction between G protein and PKC-ε underlies the impaired myocardial response to ischemic preconditioning in postinfarct remodeled hearts

    We have recently shown that the protective mechanism of ischemic preconditioning (PC) is impaired in the myocardium that survived infarction and underwent postinfarct ventricular remodeling. In this study, we ...

    Takayuki Miki, Tetsuji Miura, Masaya Tanno… in Molecular and Cellular Biochemistry (2003)

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    Chapter

    Bradykinin and Preconditioning Against Infarction

    Bradykinin is a peptide consisting of nine amino acids, which is generated by the plasma kallikrein-kinin system as well as the glandular (tissue) kallikrein-kinin system and plasma aminopeptidase (Fig. 11-1)....

    Tetsuji Miura, Jun Sakamoto, Takayuki Miki in Adenosine, Cardioprotection and Its Clinic… (1997)