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  1. Article

    Open Access

    SARIFA as a new histopathological biomarker is associated with adverse clinicopathological characteristics, tumor-promoting fatty-acid metabolism, and might predict a metastatic pattern in pT3a prostate cancer

    Recently, we introduced Stroma-AReactive-Invasion-Front-Areas (SARIFA) as a novel hematoxylin–eosin (H&E)-based histopathologic prognostic biomarker for various gastrointestinal cancers, closely related to lip...

    Johanna S. Enke, Matthias Groß, Bianca Grosser, Eva Sipos, Julie Steinestel in BMC Cancer (2024)

  2. Article

    Open Access

    The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

    Up to 50% of penile squamous cell carcinomas (pSCC) develop in the context of high-risk human papillomavirus (HR-HPV) infection. Most of these tumours have been reported to show basaloid differentiation and ov...

    Julie Steinestel, Andreas Al Ghazal, Annette Arndt, Thomas J Schnoeller in BMC Cancer (2015)

  3. Article

    Open Access

    Positive surgical margins in nephron-sparing surgery: risk factors and therapeutic consequences

    The increased use of nephron-sparing surgery to treat localized renal cell carcinoma (RCC) lends weight to the question of the value of microscopically positive surgical margins (PSM) in cases with a tumor bed...

    Julie Steinestel, Sandra Steffens, Konrad Steinestel in World Journal of Surgical Oncology (2014)

  4. Article

    Open Access

    Survival advantage of partial over radical nephrectomy in patients presenting with localized renal cell carcinoma

    Partial nephrectomy (PN) preserves renal function and has become the standard approach for T1a renal cell carcinoma (RCC). However, there is still an ongoing debate as to which patients will actually derive gr...

    Frederik C Roos, Sandra Steffens, Kerstin Junker, Martin Janssen in BMC Cancer (2014)

  5. Article

    Open Access

    High CRP values predict poor survival in patients with penile cancer

    High levels of circulating C-reactive protein (CRP) have recently been linked to poor clinical outcome in various malignancies. The aim of this study was to evaluate the prognostic significance of the preopera...

    Sandra Steffens, Andreas Al Ghazal, Julie Steinestel, Rieke Lehmann in BMC Cancer (2013)