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  1. Article

    Open Access

    Prebiotic fibre mixtures counteract the manifestation of gut microbial dysbiosis induced by the chemotherapeutic 5-Fluorouracil (5-FU) in a validated in vitro model of the colon

    5-Fluorouracil (5-FU) is used as an antineoplastic agent in distinct cancer types. Increasing evidence suggests that the gut microbiota might modulate 5-FU efficacy and toxicity, potentially affecting the pati...

    Janine Ziemons, Lars E. Hillege, Romy Aarnoutse, Judith de Vos-Geelen in BMC Microbiology (2024)