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Open AccessCorrection to: Characteristics of splenic PD-1+ γδT cells in Plasmodium yoelii nigeriensis infection
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Open AccessCharacteristics of splenic PD-1+ γδT cells in Plasmodium yoelii nigeriensis infection
Although the functions of programmed death-1 (PD-1) on αβ T cells have been extensively reported, a role for PD-1 in regulating γδT cell function is only beginning to emerge. Here, we investigated the phenotyp...
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Open AccessRevisiting the role of pregnancy zone protein (PZP) as a cancer biomarker in the immunotherapy era
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Open AccessCold-induced FOXO1 nuclear transport aids cold survival and tissue storage
Cold-induced injuries severely limit opportunities and outcomes of hypothermic therapies and organ preservation, calling for better understanding of cold adaptation. Here, by surveying cold-altered chromatin a...
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Retraction Note: Two Mixed-Ligand Co(II)-Based Coordination Polymers: Application Value in the Later Rehabilitation of Fracture Patients by Activating WNT Signaling Pathway
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Open AccessDefects in the cell wall and its deposition caused by loss-of-function of three RLKs alter root hydrotropism in Arabidopsis thaliana
Root tips can sense moisture gradients and grow into environments with higher water potential. This process is called root hydrotropism. Here, we report three closely related receptor-like kinases (RLKs) that ...
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Open AccessIntrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly
Carboxysomes are a paradigm of self-assembling proteinaceous organelles found in nature, offering compartmentalisation of enzymes and pathways to enhance carbon fixation. In α-carboxysomes, the disordered link...
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Open AccessSulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish
Nonsteroidal anti-inflammatory drugs compose one of the most widely used classes of medications, but the risks for early development remain controversial, especially in the nervous system. Here, we utilized ze...
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Open AccessMolecular architecture and conservation of an immature human endogenous retrovirus
The human endogenous retrovirus K (HERV-K) is the most recently acquired endogenous retrovirus in the human genome and is activated and expressed in many cancers and amyotrophic lateral sclerosis. We present t...
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Open AccessConstruction and validation of web-based nomograms for detecting and prognosticating in prostate adenocarcinoma with bone metastasis
Bone metastasis (BM) is one of the most common sites of metastasis in prostate adenocarcinoma (PA). PA with BM can significantly diminish patients’ quality of life and result in a poor prognosis. The objective...
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Open AccessStructure and activity of particulate methane monooxygenase arrays in methanotrophs
Methane-oxidizing bacteria play a central role in greenhouse gas mitigation and have potential applications in biomanufacturing. Their primary metabolic enzyme, particulate methane monooxygenase (pMMO), is hou...
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Size matters: Steric hindrance of precursor molecules controlling the evolution of CdSe magic-size clusters and quantum dots
Little is known about how to precisely promote the selective production of either colloidal semiconductor metal chalcogenide (ME), magic-size clusters (MSCs), or quantum dots (QDs). Recently, a two-pathway mod...
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Open AccessTitanium nanosheet as robust and biosafe drug carrier for combined photochemo cancer therapy
Two-dimensional (2D) Titanium nanosheets (Ti NSs) have shown many excellent properties, such as nontoxicity, satisfactory photothermal conversion efficacy, etc. However, the biomedical applications of Ti NSs h...
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Open AccessAstragaloside IV protects human cardiomyocytes from hypoxia/reoxygenation injury by regulating miR-101a
Astragaloside IV (AS/IV) is one of the extracted components from the traditional Chinese medicine Astragalus which has been demonstrated to have potential capacity for anti-inflammation activity and for treati...
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Open AccessA Survey of the FDA’s Adverse Event Reporting System Database Concerning Urogenital Tract Infections and Sodium Glucose Cotransporter‐2 Inhibitor Use
We tested the possible association between sodium glucose cotransporter-2 inhibitor (SGLT-2i) use and urogenital tract infection (UTI) occurrences by assessing the publicly available US Food and Drug Administr...
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Open AccessAdvances in bio-active constituents, pharmacology and clinical applications of rhubarb
Rhubarb is one of the most ancient, commonly used and important herbs in Chinese medicine. The modern researches of rhubarb clarified the efficacies, ingredients and mechanisms in a more scientific and rigorou...
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Open AccessNMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury
Damage-associated molecular patterns (DAMP) trigger innate immune response and exacerbate inflammation to combat infection and cellular damage. Identifying DAMPs and revealing their functions are thus of cruci...
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Open AccessDetection of IL-9 producing T cells in the PBMCs of allergic asthmatic patients
Interleukin-9 (IL-9) was reported as an active participant in the pathogenesis of allergic asthma. This study aimed to investigate the major source ofIL-9 and its effect on interferon γ (IFN-γ) and immunoglobu...
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Open AccessPerformance of genetic risk factors in prediction of trichloroethylene induced hypersensitivity syndrome
Trichloroethylene induced hypersensitivity syndrome is dose-independent and potentially life threatening disease, which has become one of the serious occupational health issues and requires intensive treatment...
