5 Result(s)
within
Ju-fang Huang
Biomedicine
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Article
The Toxic Effect of ALLN on Primary Rat Retinal Neurons
N-acetyl-leucyl-leucyl-norleucinal (ALLN), an inhibitor of proteasomes and calpain, is widely used to reduce proteasomes or calpain-mediated cell death in rodents. However, ALLN is toxic ...
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Article
Open AccessReceptor interacting protein 3-induced RGC-5 cell necroptosis following oxygen glucose deprivation
Necroptosis is a type of regulated form of cell death that has been implicated in the pathogenesis of various diseases. Receptor-interacting protein 3 (RIP3), a member of the RIP family of proteins, has been r...
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Article
Open AccessCalpain: a molecule to induce AIF-mediated necroptosis in RGC-5 following elevated hydrostatic pressure
RIP3 (Receptor-interacting protein 3) pathway was mainly described as the molecular mechanism of necroptosis (programmed necrosis). But recently, non-RIP3 pathways were found to mediate necroptosis. We deliber...
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Article
Open AccessDifferential neuronal expression of receptor interacting protein 3 in rat retina: involvement in ischemic stress response
Receptor-interacting protein 3 (RIP3), a member of RIP family proteins, has been shown to participate in programmed necrosis or necroptosis in cell biology studies. Evidence suggests that necroptosis may be a ...
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Article
Open AccessElevation of soluble major histocompatibility complex class I related chain A protein in malignant and infectious diseases in Chinese patients
Elevation of soluble major histocompatibility complex class I chain-related gene A (sMICA) products in serum has been linked to tissue/organ transplantation, autoimmune diseases and some malignant disorders. C...
