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  1. No Access

    Article

    Exploring the genetic overlap between twelve psychiatric disorders

    The widespread comorbidity among psychiatric disorders demonstrated in epidemiological studies1–5 is mirrored by non-zero, positive genetic correlations from large-scale genetic studies6–10. To identify shared bi...

    Cato Romero, Josefin Werme, Philip R. Jansen, Joel Gelernter… in Nature Genetics (2022)

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    Article

    An integrated framework for local genetic correlation analysis

    Genetic correlation (rg) analysis is used to identify phenotypes that may have a shared genetic basis. Traditionally, rg is studied globally, considering only the average of the shared signal across the genome, a...

    Josefin Werme, Sophie van der Sluis, Danielle Posthuma… in Nature Genetics (2022)