5 Result(s)
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Article
Open AccessFunctional connectivity of cognition-related brain networks in adults with fetal alcohol syndrome
Fetal alcohol syndrome (FAS) can result in cognitive dysfunction. Cognitive functions affected are subserved by few functional brain networks. Functional connectivity (FC) in these networks can be assessed wit...
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Article
Metabolic control during the neonatal period in phenylketonuria: associations with childhood IQ
In phenylketonuria, treatment and subsequent lowering of phenylalanine levels usually occur within the first month of life. This study investigated whether different indicators of metabolic control during the ...
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Article
Phenylketonuria: No Specific Frontal Lobe-Dependent Neuropsychological Deficits of Early-Treated Patients in Comparison with Diabetics
Neuropsychologic studies have shown that even phenylketonuric patients treated early suffer from phenylalanine-related deficits in all age periods, from childhood to adulthood. This study was performed to dete...
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Normal Clinical Outcome in Untreated Subjects with Mild Hyperphenylalaninemia
There is international consensus that patients with phenylalanine (Phe) levels <360 μM on a free diet do not need Phe-lowering dietary treatment whereas patients with levels >600 μM do. Clinical outcome of pat...
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Article
252 INTELLECTUAL OUTCOME AND CRANIAL MRI-FINDINGS IN PATIENTS WITH PERSISTENT HYPERPHENYLALANINEHIA (HPA)
The intellectual outcome of patients with HPA (serum phe levels under free diet < 600 μmol/l) was not systematically studied so far. Therefore we tested 31 patients (age: 22 ± 4 years) for IQ (WAIS-R) and scho...
