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Open AccessIdentification of the major photodegradant in metronidazole by LC-PDA-MS and its reveal in compendial methods
Metronidazole in aqueous solution is sensitive to light and UV irradiation, leading to the formation of N-(2-hydroxyethyl)-5-methyl-l,2,4-oxadiazole-3-carboxamide. This is revealed here by liquid chromatography w...