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  1. Article

    Open Access

    Efficacy of anti-PD-1 therapy in patients with melanoma brain metastases

    There is limited data on the efficacy of anti-programmed death 1 (PD-1) antibodies in patients (pts) with melanoma brain metastasis (BM), particularly those which are symptomatic.

    Sagun Parakh, John J Park, Shehara Mendis, Rajat Rai, Wen Xu in British Journal of Cancer (2017)

  2. Article

    Open Access

    Protein kinase inhibitor responses in uveal melanoma reflects a diminished dependency on PKC-MAPK signaling

    Uveal melanoma (UM) is a rare cancer arising from melanocytes in the uveal tract of the eye. Despite effective primary treatment, there is no approved therapy for metastatic UM and prognosis and survival remai...

    John J. Park, Ashleigh Stewart, Mal Irvine, Bernadette Pedersen in Cancer Gene Therapy (2022)

  3. Article

    Open Access

    A first-in-human phase 1 study of nofazinlimab, an anti-PD-1 antibody, in advanced solid tumors and in combination with regorafenib in metastatic colorectal cancer

    We assessed nofazinlimab, an anti-PD-1 antibody, in solid tumors and combined with regorafenib in metastatic colorectal cancer (mCRC).

    Daphne Day, John J. Park, Jermaine Coward, Ben Markman in British Journal of Cancer (2023)