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  1. Article

    Open Access

    MYB-NFIB gene fusions identified in archival adenoid cystic carcinoma tissue employing NanoString analysis: an exploratory study

    Adenoid cystic carcinoma (ACC) is a slow growing salivary gland malignancy that is molecularly characterized by t(6:9)(q22–23;p23–24) translocations which predominantly result in MYB-NFIB gene fusions in nearly h...

    John B. McIntyre, Jenny J. Ko, Jodi Siever, Angela M. Y. Chan… in Diagnostic Pathology (2019)

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    Article

    Endogenous sex hormone exposure and repetitive element DNA methylation in healthy postmenopausal women

    Epigenetic mechanisms may help to explain the complex and heterogeneous relation between sex hormones and cancer. Few studies have investigated the effects of sex hormones on epigenetic markers related to canc...

    Devon J. Boyne, Christine M. Friedenreich, John B. McIntyre… in Cancer Causes & Control (2017)

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    Article

    Determination of the methylation status of MGMT in different regions within glioblastoma multiforme

    Epigenetic silencing of the MGMT gene through promoter methylation correlates with improved survival in Glioblastoma Multiforme (GBM) patients receiving concurrent chemoradiotherapy. Although the clinical benefit...

    Mark G. Hamilton, Gloria Roldán, Anthony Magliocco… in Journal of Neuro-Oncology (2011)

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    Article

    Toxicity from chemoradiotherapy in older patients with glioblastoma multiforme

    Introduction Elderly patients have glioblastomas (GBM) that are aggressive and poorly responsive to treatment. They are also prone to the side effects of treatment of GBM. Methods To shed...

    Angelique E. Sijben, John B. McIntyre, Gloria B. Roldán… in Journal of Neuro-Oncology (2008)