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Open AccessAre different stoichiometries feasible for complexes between lymphotoxin-alpha and tumor necrosis factor receptor 1?
Tumor necrosis factors, TNF and lymphotoxin-α (LT), are cytokines that bind to two receptors, TNFR1 and TNFR2 (TNF-receptor 1 and 2) to trigger their signaling cascades. The exact mechanism of ligand-induced r...