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Open AccessPublisher Correction: HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
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Open AccessHIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
The hypoxia-inducible factors (HIFs) regulate the main transcriptional pathway of response to hypoxia in T cells and are negatively regulated by von Hippel-Lindau factor (VHL). But the role of HIFs in the regu...
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Open AccessAuthor Correction: A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
In the originally published version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include support to Thomas Perlmann provide...
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Article
Open AccessNexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP
Nexilin, encoded by the NEXN gene, is expressed in striated muscle and localizes to Z-discs, influencing mechanical stability. We examined Nexilin/NEXN in smooth muscle cells (SMCs), and addressed if Nexilin loca...
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Open AccessA comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons
The brain is composed of hundreds of different neuronal subtypes, which largely retain their identity throughout the lifespan of the organism. The mechanisms governing this stability are not fully understood, ...
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Article
Open AccessPotent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin α2 chain-deficient muscular dystrophy
A large number of human diseases are caused by chronic tissue injury with fibrosis potentially leading to organ failure. There is a need for more effective anti-fibrotic therapies. Congenital muscular dystroph...
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Regulation of repulsion versus adhesion by different splice forms of an Eph receptor
Eph tyrosine kinase receptors and their membrane-bound ephrin ligands mediate cell interactions and participate in several developmental processes1,2,3,4. Ligand binding to an Eph receptor results in tyrosine pho...