4 Result(s)
within
Joel T. Dunn
Medicine & Public Health
Imaging / Radiology
Oncology
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Article
Open AccessEvaluation of [ 13 N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain
The conversion of synaptic glutamate to glutamine in astrocytes by glutamine synthetase (GS) is critical to maintaining healthy brain activity and may be disrupted in several brain disorders. As the GS catalys...
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Article
Open AccessDefining the optimal method for measuring baseline metabolic tumour volume in diffuse large B cell lymphoma
Metabolic tumour volume (MTV) is a promising prognostic indicator in diffuse large B cell lymphoma (DLBCL). Optimal thresholds to divide patients into ‘low’ versus ‘high’ MTV groups depend on clinical characte...
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Article
Open AccessCombination of baseline metabolic tumour volume and early response on PET/CT improves progression-free survival prediction in DLBCL
The study objectives were to assess the prognostic value of quantitative PET and to test whether combining baseline metabolic tumour burden with early PET response could improve predictive power in DLBCL.
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Article
Open AccessAssessing radiotracer kinetics in the Langendorff perfused heart
The Langendorff perfused heart is a physiologically relevant and controllable model with potential for assessing the pharmacokinetics of new radiotracers under a range of pathophysiological conditions.. We ass...
