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  1. No Access

    Article

    The clinical relevance of various methods of classifying ipsilateral breast tumour recurrence as either true local recurrence or new primary

    Describes the relevance of –various classification methods for ipsilateral breast tumour recurrence (IBTR) as either true recurrence (TR) or new primary (NP) on both disease-specific survival (DSS) and distant...

    Jan J. Jobsen, Henk Struikmans, Ester Siemerink in Breast Cancer Research and Treatment (2022)

  2. No Access

    Article

    Clinical relevance of the timing of radiotherapy after breast-conserving surgery

    To investigate the effect of the timing of radiation therapy after breast-conserving surgery in relation to distant metastasis-free survival and disease-specific survival.

    Jan J. Jobsen PhD, Henk Struikmans, Job van der Palen in Strahlentherapie und Onkologie (2022)

  3. No Access

    Article

    The Mitotic Activity Index in combination with Her2neu: a strong prognosticator in breast cancer

    The aim of this study is to evaluate the prognostic value of the Mitotic Activity Index (MAI) in combination with the human epidermal growth factor receptor (Her2) for distant metastases-free survival (DMFS) a...

    Jan J. Jobsen, Henk Struikmans, Job van der Palen in Breast Cancer Research and Treatment (2020)

  4. Article

    Open Access

    Effect of weight loss, with or without exercise, on body composition and sex hormones in postmenopausal women: the SHAPE-2 trial

    Physical inactivity and overweight are risk factors for postmenopausal breast cancer. The effect of physical activity may be partially mediated by concordant weight loss. We studied the effect on serum sex hor...

    Willemijn AM. van Gemert, Albertine J. Schuit, Job van der Palen in Breast Cancer Research (2015)

  5. No Access

    Article

    The prognostic relevance of the mitotic activity index in axillary lymph node-negative breast cancer

    The aim of the present study is to look at the mitotic activity index (MAI) as a prognostic factor in a prospective population-based cohort of lymph node-negative invasive breast cancer patients. Analyses wer...

    Jan J. Jobsen, Job van der Palen, Mariël Brinkhuis in Breast Cancer Research and Treatment (2015)

  6. Article

    Open Access

    Design of the SHAPE-2 study: the effect of physical activity, in addition to weight loss, on biomarkers of postmenopausal breast cancer risk

    Physical inactivity and overweight are two known risk factors for postmenopausal breast cancer. Former exercise intervention studies showed that physical activity influences sex hormone levels, known to be rel...

    Willemijn AM van Gemert, Jolein I Iestra, Albertine J Schuit, Anne M May in BMC Cancer (2013)

  7. Article

    Open Access

    Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer

    The presence of circulating tumor cells (CTC) is an independent prognostic factor for progression-free survival and breast cancer-related death (BRD) for patients with metastatic breast cancer beginning a new ...

    Bas Franken, Marco R de Groot, Walter JB Mastboom, Istvan Vermes in Breast Cancer Research (2012)

  8. No Access

    Article

    Timing of radiotherapy and survival benefit in breast cancer

    To look at the optimum timing of radiotherapy in breast-conserving therapy (BCT) in relation to outcome in breast cancer.

    Jan J. Jobsen, Job van der Palen, Francisca Ong in Breast Cancer Research and Treatment (2006)