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  1. Article

    Open Access

    Does immediate smart feedback on therapy adherence and inhalation technique improve asthma control in children with uncontrolled asthma? A study protocol of the IMAGINE I study

    Many asthmatic children suffer from uncontrolled asthma with frequent exacerbations, despite an optimal treatment plan using inhalation medication. Studies have shown that therapy adherence and inhalation tech...

    Esther T. Sportel, Martijn J. Oude Wolcherink, Job van der Palen, Anke Lenferink in Trials (2020)

  2. Article

    Open Access

    Asthma control and COPD symptom burden in patients using fixed-dose combination inhalers (SPRINT study)

    Previous studies have found suboptimal control of symptom burden to be widespread among patients with asthma and chronic obstructive pulmonary disease (COPD). The Phase IV SPRINT study was conducted in 10 coun...

    Nicolas Roche, Vicente Plaza, Vibeke Backer in npj Primary Care Respiratory Medicine (2020)

  3. Article

    Open Access

    Effect of diet with or without exercise on abdominal fat in postmenopausal women – a randomised trial

    We assessed the effect of equivalent weight loss with or without exercise on (intra-) abdominal fat in postmenopausal women in the SHAPE-2 study.

    Willemijn A. van Gemert, Petra H. Peeters, Anne M. May in BMC Public Health (2019)

  4. Article

    Open Access

    Systematic review of association between critical errors in inhalation and health outcomes in asthma and COPD

    Inhaled medications are the cornerstone of treatment and management of asthma and COPD. However, inhaler device errors are common among patients and have been linked with reduced symptom control, an increased ...

    Janwillem W. H. Kocks, Henry Chrystyn in npj Primary Care Respiratory Medicine (2018)

  5. Article

    Open Access

    Device errors in asthma and COPD: systematic literature review and meta-analysis

    Inhaler device errors are common and may impact the effectiveness of the delivered drug. There is a paucity of up-to-date systematic reviews (SRs) or meta-analyses (MAs) of device errors in asthma and chronic ...

    Henry Chrystyn, Job van der Palen, Raj Sharma in npj Primary Care Respiratory Medicine (2017)

  6. Article

    Open Access

    Erratum: A randomised open-label cross-over study of inhaler errors, preference and time to achieve correct inhaler use in patients with COPD or asthma: comparison of ELLIPTA with other inhaler devices

    Correction to: npj Primary Care Respiratory Medicine (2016) 26, 16079; doi:10.1038/npjpcrm.2016.79; published online 24 November 2016 In the original version of the article, there were typographical errors tha...

    Job van der Palen, Mike Thomas, Henry Chrystyn in npj Primary Care Respiratory Medicine (2017)

  7. Article

    Open Access

    A randomised open-label cross-over study of inhaler errors, preference and time to achieve correct inhaler use in patients with COPD or asthma: comparison of ELLIPTA with other inhaler devices

    Errors in the use of different inhalers were investigated in patients naive to the devices under investigation in a multicentre, single-visit, randomised, open-label, cross-over study. Patients with chronic ob...

    Job van der Palen, Mike Thomas, Henry Chrystyn in npj Primary Care Respiratory Medicine (2016)

  8. Article

    Open Access

    Association of Psychiatric History and Type D Personality with Symptoms of Anxiety, Depression, and Health Status Prior to ICD Implantation

    Personality factors and psychiatric history may help explain individual differences in risk of psychological morbidity and poor health outcomes in patients with an implantable cardioverter defibrillator (ICD).

    Annemieke H. Starrenburg, Karin Kraaier in International Journal of Behavioral Medici… (2013)

  9. Article

    Open Access

    Design of the SHAPE-2 study: the effect of physical activity, in addition to weight loss, on biomarkers of postmenopausal breast cancer risk

    Physical inactivity and overweight are two known risk factors for postmenopausal breast cancer. Former exercise intervention studies showed that physical activity influences sex hormone levels, known to be rel...

    Willemijn AM van Gemert, Jolein I Iestra, Albertine J Schuit, Anne M May in BMC Cancer (2013)