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  1. Article

    Open Access

    TaqTth-hpRNA: a novel compact RNA-targeting tool for specific silencing of pathogenic mRNA

    Pathogenic allele silencing is a promising treatment for genetic hereditary diseases. Here, we develop an RNA-cleaving tool, TaqTth-hpRNA, consisting of a small, chimeric TaqTth, and a hairpin RNA guiding prob...

    Chong Xu, Jiyanuo Cao, Huanran Qiang, Yu Liu, Jialin Wu, Qiudan Luo… in Genome Biology (2024)

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