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Article
Open AccessSearching for SNPs with cloud computing
As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bow...
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Article
Open AccessIs searching full text more effective than searching abstracts?
With the growing availability of full-text articles online, scientists and other consumers of the life sciences literature now have the ability to go beyond searching bibliographic records (title, abstract, me...
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Article
Open AccessPageRank without hyperlinks: Reranking with PubMed related article networks for biomedical text retrieval
Graph analysis algorithms such as PageRank and HITS have been successful in Web environments because they are able to extract important inter-document relationships from manually-created hyperlinks. We conside...
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Article
Open AccessIdentification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivated by increasing evidence that some DNA reg...
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Article
Open AccessPubMed related articles: a probabilistic topic-based model for content similarity
We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document is about a particular topic is computed from ...