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The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT

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  1. Article

    Open Access

    Searching for SNPs with cloud computing

    As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bow...

    Ben Langmead, Michael C Schatz, Jimmy Lin, Mihai Pop, Steven L Salzberg in Genome Biology (2009)

  2. Article

    Open Access

    Is searching full text more effective than searching abstracts?

    With the growing availability of full-text articles online, scientists and other consumers of the life sciences literature now have the ability to go beyond searching bibliographic records (title, abstract, me...

    Jimmy Lin in BMC Bioinformatics (2009)

  3. Article

    Open Access

    PageRank without hyperlinks: Reranking with PubMed related article networks for biomedical text retrieval

    Graph analysis algorithms such as PageRank and HITS have been successful in Web environments because they are able to extract important inter-document relationships from manually-created hyperlinks. We conside...

    Jimmy Lin in BMC Bioinformatics (2008)

  4. Article

    Open Access

    Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors

    Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivated by increasing evidence that some DNA reg...

    Xue** Yu, Jimmy Lin, Donald J Zack, Jiang Qian in BMC Bioinformatics (2007)

  5. Article

    Open Access

    PubMed related articles: a probabilistic topic-based model for content similarity

    We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document is about a particular topic is computed from ...

    Jimmy Lin, W John Wilbur in BMC Bioinformatics (2007)