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Article
LncRNA DINOR is a virulence factor and global regulator of stress responses in Candida auris
The emergent fungal pathogen Candida auris exhibits high resistance to antifungal drugs and environmental stresses, impeding treatment and decontamination1–3. The fungal factors mediating this stress tolerance ar...
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Article
Genome-wide piggyBac transposon-based mutagenesis and quantitative insertion-site analysis in haploid Candida species
Invasive fungal infections caused by Candida species are life threatening with high mortality, posing a severe public health threat. New technologies for rapid, genome-wide identification of virulence genes and t...
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Article
Role of Ppt1 in multiple stress responses in Candida albicans
To study the function of CaPpt1, we deleted PPT1 gene from the Candida albicans genome by sequentially replacing the entire coding region with the selectable markers ARG4 and HIS1. The results showed that the del...