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  1. Article

    Telomere and telomerase in oncology

    Shortening of the telomeric DNA at the chromosome ends is presumed to limit the lifespan of human cells and elicit a signal for the onset of cellular senescence. To continually proliferate across the senescent...

    Jiao MU, Li **n WEI in Cell Research (2002)

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  2. Article

    Open Access

    Down-regulation of SLC25A20 promotes hepatocellular carcinoma growth and metastasis through suppression of fatty-acid oxidation

    Solute carrier family 25 member 20 (SLC25A20) is a mitochondrial-membrane–carrier protein involved in the transport of acylcarnitines into mitochondrial matrix for oxidation. A previous-integrated-proteogenomi...

    Peng Yuan, Jiao Mu, Zijun Wang, Shuaijun Ma, **uwei Da, Jian Song… in Cell Death & Disease (2021)

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    Article

    Mitochondrial transcription factor B1 promotes the progression of hepatocellular carcinoma via enhancing aerobic glycolysis

    Mitochondrial dysfunctions play crucial roles in the carcinogenesis of various human cancers. However, the molecular mechanisms leading to mitochondrial dysfunction and thus cancer progression remains largely ...

    Jiao Mu, Yiyuan Tian, Fengzhou Liu… in Journal of Cell Communication and Signaling (2022)

  4. No Access

    Article

    Circ-IP6K2 suppresses tumor progression by modulating the miR-1292-5p/CAMK2N1 signal in clear cell renal cell carcinoma

    Renal cell carcinoma (RCC) is a malignant tumor originating from the epithelial cells of the renal tubules. The clear cell RCC subtype is closely linked to a poor prognosis due to its rapid progression. Circul...

    Jian-ying Tang, Lu Yang, Qing-Jian Wu, Ying Yang… in Functional & Integrative Genomics (2024)