249 Result(s)
within
Jianming **e
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessApplication of citric acid can enhance the accuracy for 13C-urea breath tests in the diagnosis of Helicobacter pylori infection in Chinese patients
Previous published data have confirmed that the addition of a citric acid meal improves the accuracy of the 13C-urea breath test (13C-UBT). However, some studies have suggested that a citric acid test meal may no...
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Open AccessJag1/2 maintain esophageal homeostasis and suppress foregut tumorigenesis by restricting the basal progenitor cell pool
Basal progenitor cells are crucial for maintaining foregut (the esophagus and forestomach) homeostasis. When their function is dysregulated, it can promote inflammation and tumorigenesis. However, the mechanis...
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Agricultural management practices in China enhance nitrogen sustainability and benefit human health
The potential of enhanced agricultural management practices to drive sustainability is rarely quantified at grassroots level. Here we analyse nitrogen use and loss in Chinese cropland, drawing from data collec...
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Open AccessIn vivo evaluation of safety and performance of a tapered nitinol venous stent with inclined proximal end in an ovine iliac venous model
A tapered stent with inclined proximal end is designed for fitting the iliac anatomically. The aim of the present study was to evaluate the safety and performance of the new stent in ovine left iliac veins. Th...
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Open AccessIdentity-based controlled delegated outsourcing data integrity auditing scheme
With the continuous development of cloud computing, the application of cloud storage has become more and more popular. To ensure the integrity and availability of cloud data, scholars have proposed several clo...
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Open AccessBet hedging in a unicellular microalga
Understanding how organisms have adapted to persist in unpredictable environments is a fundamental goal in biology. Bet hedging, an evolutionary adaptation observed from microbes to humans, facilitates reprodu...
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Managing fragmented croplands for environmental and economic benefits in China
Cropland fragmentation contributes to low productivity and high abandonment risk. Using spatial statistics on a detailed land use map, we show that 10% of Chinese croplands have no potential to be consolidated...
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Open AccessLeukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice
Cancer cachexia is a systemic metabolic syndrome characterized by involuntary weight loss, and muscle and adipose tissue wasting. Mechanisms underlying cachexia remain poorly understood. Leukemia inhibitory fa...
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Open AccessA chromosome-level genome assembly of the Echiura Urechis unicinctus
Echiura is a distinctive family of unsegmented sausage-shaped marine worms whose phylogenetic relationship still needs strong evidence from the phylogenomic analysis. In this family, Urechis unicinctus is known f...
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Open AccessReplicating shear-mediated self-assembly of spider silk through microfluidics
The development of artificial spider silk with properties similar to native silk has been a challenging task in materials science. In this study, we use a microfluidic device to create continuous fibers based ...
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Open AccessCobalt-free composite-structured cathodes with lithium-stoichiometry control for sustainable lithium-ion batteries
Lithium-ion batteries play a crucial role in decarbonizing transportation and power grids, but their reliance on high-cost, earth-scarce cobalt in the commonly employed high-energy layered Li(NiMnCo)O2 cathodes r...
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Open AccessManaging urban development could halve nitrogen pollution in China
Halving nitrogen pollution is crucial for achieving Sustainable Development Goals (SDGs). However, how to reduce nitrogen pollution from multiple sources remains challenging. Here we show that reactive nitroge...
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Open Accessp53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome
Radiation-induced gastrointestinal syndrome is a major complication and limiting factor for radiotherapy. Tumor suppressor p53 has a protective role in radiation-induced gastrointestinal toxicity. However, its...
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Open AccessCovalent PARylation of DNA base excision repair proteins regulates DNA demethylation
The intracellular ATP-ribosyltransferases PARP1 and PARP2, contribute to DNA base excision repair (BER) and DNA demethylation and have been implicated in epigenetic programming in early mammalian development. ...
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Open AccessMetallic micronutrients are associated with the structure and function of the soil microbiome
The relationship between metallic micronutrients and soil microorganisms, and thereby soil functioning, has been little explored. Here, we investigate the relationship between metallic micronutrients (Fe, Mn, ...
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Open AccessAuthor Correction: A genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources
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Open AccessDesign and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor
Despite the increasing number of GPCR structures and recent advances in peptide design, the development of efficient technologies allowing rational design of high-affinity peptide ligands for single GPCRs rema...
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Open AccessA computational spatial whole-Cell model for hepatitis B viral infection and drug interactions
Despite a vaccine, hepatitis B virus (HBV) remains a world-wide source of infections and deaths. We develop a whole-cell computational platform combining spatial and kinetic models describing the infection cyc...
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Open AccessA genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources
Soil harbors a vast expanse of unidentified microbes, termed as microbial dark matter, presenting an untapped reservoir of microbial biodiversity and genetic resources, but has yet to be fully explored. In thi...
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Open AccessThe effect of soil environmental factors on the yield and quality of Pueraria lobata
Pueraria lobata is a typical medicinal and edible plant with great market value and demand, thus exploring the relationship between soil environmental factors and the yield and quality of Pueraria lobata is of gr...
